UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 14A
PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE
SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. )
Filed by the Registrant x
Filed by a Party other than the Registrant o
Check the appropriate box:
o    Preliminary Proxy Statement
o    Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2))
x    Definitive Proxy Statement
o    Definitive Additional Materials
o    Soliciting Material Pursuant to §240.14a-12
VITAL THERAPIES, INC.

(Name of Registrant as Specified In Its Charter)


(Name of Person(s) Filing Proxy Statement, if other than the Registrant)
Payment of Filing Fee (Check the appropriate box):
x    No fee required.
o    Fee computed on table below per Exchange Act Rules 14a‑6(i)(1) and 0‑11.
(1)    Title of each class of securities to which transaction applies:


(2)    Aggregate number of securities to which transaction applies:


UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 14A

PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE
SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. )

Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐ Preliminary Proxy Statement

☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

☒ Definitive Proxy Statement

☐ Definitive Additional Materials

☐ Soliciting Material Pursuant to §240.14a-12

IMMUNIC, INC.

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)
Payment of Filing Fee (Check the appropriate box):

☒ No fee required.

☐ Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

(1)

Title of each class of securities to which transaction applies

(2)

Aggregate number of securities to which transaction applies:

(3)

Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11
(set forth the amount on which the filing fee is calculated and state how it was determined):



(4)    Proposed maximum aggregate value of transaction:


(5)    Total fee paid:


o    Fee paid previously with preliminary materials.

o(4)

Proposed maximum aggregate value of transaction:

(5)

Total fee paid:

Fee paid previously with preliminary materials.
☐ Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.
(1)    (1)

Amount Previously Paid:

(2)

Form, Schedule or Registration Statement No.:

(3)

Filing Party:

(4)Date Filed:



(2)    Form, Schedule or Registration Statement No.:



(3)    Filing Party:


(4)    Date Filed:







image1a02.jpg
15010

Immunic Therapeutics

1200 Avenue of Science,the Americas, Suite 200

San Diego, California 92128
(858) 673-6840

New York, New York 10036

To our Stockholders:


We are pleased to invite you to attend the annual meeting of stockholders of Vital Therapies,Immunic, Inc. (“Immunic” or the “Company”), to be held on Wednesday, May 23, 2018July 2, 2020 at 8:0030 a.m., Pacific Time, Eastern time, virtually via the Internet at 12235 El Camino Real, San Diego, CA 92130.

https://web.lumiagm.com/276702602. The annual stockholders meeting will be a completely virtual and will be conducted exclusively by webcast on the internet. No physical meeting will be held.

Details regarding how to attend the annual meeting and the business to be conducted at the annual meeting are more fully described in the accompanying notice of annual meeting of stockholders and proxy statement.

Your vote is important. Regardless of whether you plan to attend the annual meeting, it is important that your shares be represented and voted at the annual meeting, and we hope you will vote as soon as possible. You may vote by proxy over the Internet or by telephone or, if you received paper copies of the proxy materials by mail, you may also vote by mail by following the instructions on the proxy card or voting instruction card. Voting over the Internet or by telephone, written proxy or voting instruction card will ensure your representation at the annual meeting regardless of whether you attend the annual meeting.

Thank you for your ongoing support of, and continued interest in, Vital Therapies,Immunic, Inc.

Sincerely,

  
russcoxsignature.jpg
faheemsignature.jpg
Russell J. CoxFaheem Hasnain
Dr. Daniel Vitt
Chief Executive Officer
Dr. Duane Nash
Executive Chairman of the Board of Directors

New York, New York

May 4, 2020

San Diego, California

April 11, 2018




VITAL THERAPIES,

IMMUNIC, INC.

15010

1200 Avenue of Science,the Americas, Suite 200

San Diego, California 92128
(858) 673-6840

New York, New York 10036

NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

Time and Date8:0030 a.m., Pacific Time, Eastern time, on Wednesday, May 23, 2018July 2, 2020
Place12235 El Camino Real, San Diego, CA 92130
PlaceVirtually via the Internet at https://web.lumiagm.com/276702602. No physical meeting will be held.
Items of Business

(1) To elect Dr. Vincent Ossipow and Mr. Jan Van den Bossche as Class I directors the three nomineesnamed in the accompanying proxy statementIII Directors to serve until our 20212023 annual meeting of stockholders and until their respective successors are duly elected and qualified.


(2) To ratify the appointment of PricewaterhouseCoopersBaker Tilly Virchow Krause, LLP (“Baker Tilly”) as our independent registered public accounting firm for the fiscal year ending December 31, 2018.


2020.

(3) To transact other business that may properly come before the annual meeting.

Adjournments and Postponements
Any action on the items of business described above may be considered at the annual meeting at the time and on the date specified above or at any time and date to which the annual meeting may be properly adjourned or postponed.

Record DateMarch 29, 2018

April 15, 2020

Only stockholders of record of our common stock as of March 29, 2018April 15, 2020 are entitled to notice of and to vote at the annual meeting.

Meeting AdmissionYou are invited to attend the annual meeting if you are a stockholder of record or a beneficial owner of shares of our common stock, in each case, as of March 29, 2018.April 15, 2020. If you are a stockholder of record, you must present valid government-issued photo identification (e.g., driver’s licenseuse your 16-digit control number included on your notice, on your proxy card or passport) for admissionon the instructions that accompanied your proxy materials, to enter the annual meeting.Annual Meeting. If you are not a stockholder of record but hold shares as a beneficial owner of shares of our common stock,in “street name,” you mustmay be required to provide proof of beneficial ownership, such ownership as of March 29, 2018 (e.g., your most recent account statement reflecting your stock ownership as of March 29, 2018) andthe record date, a copy of the voting instruction form provided by your broker, bank, trustee, or nominee, or other similar evidence of ownership. If you must present valid government-issued photo identification for admissiondo not comply with the procedures outlined above, you will not be admitted to the virtual annual meeting.
Voting
Voting

Your vote is very important. You may vote by proxy over the Internet or by telephone or, if you received paper copies of the proxy materials by mail, you may also vote by mail by following the instructions on the proxy card or voting instruction card.

For specific instructions on how to vote your shares, please refer to the section entitledQuestions and Answers About the Proxy Materials and Annual Meeting beginning on page 1 of the accompanying proxy statement.

Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting to be Held on May 23, 2018. We are furnishing proxy materials to our stockholders primarily via the Internet,


instead of mailing printed copies of those materials to each stockholder. By doing so, we save costs and reduce the environmental impact of our Annual Meeting. We will mail a Notice of Internet Availability of Proxy Materials to certain of our stockholders. This Notice contains instructions about how to access our proxy materials and vote online or vote by telephone. If you would like to receive a paper copy of our proxy materials, please follow the instructions included in the Notice of Internet Availability of Proxy Materials. If you previously chose to receive our proxy materials electronically, you will continue to receive access to these materials electronically unless you elect otherwise.

By order of the Board of Directors,

Dr. Daniel Vitt
Chief Executive Officer
New York, New York
May 4, 2020

image4a02.jpg


John M. Dunn
General Counsel and Secretary
San Diego, California
April 11, 2018




TABLE OF CONTENTS

Page

TABLE OF CONTENTS

QUESTIONS AND ANSWERS ABOUT THE PROXY MATERIALS AND ANNUAL MEETING
BOARD OF DIRECTORS AND CORPORATE GOVERNANCE6
Composition of the Board
Nominees for Director
Continuing Directors
Director Independence
Board Leadership Structure and Lead Director
Role of Board in Risk Oversight Process
Board Meetings and Committees
Compensation Committee Interlocks and Insider Participation
Considerations in Evaluating Director Nominees
Requirements for Stockholder Recommendations of a Candidate to Our Board
Communications with the Board of Directors
Director Attendance at Annual Meetings
Code of Business Conduct and Ethics
Director Compensation
Director Compensation Table
PROPOSAL NUMBER 1 ELECTION OF CLASS IIII DIRECTORS14
Nominees for Director
Required Vote
Board Recommendation
PROPOSAL NUMBER 2 RATIFICATION OF APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM15
Fees Paid to the Independent Registered Public Accounting Firm
Auditor Independence

REPORT OF THE AUDIT COMMITTEE

17
Pre-Approval Policy
Required Vote
Board Recommendation
Report of the Audit Committee
EXECUTIVE OFFICERS18
EXECUTIVE COMPENSATION20
Processes and Procedures for Executive Compensation
Summary Compensation Table
Non-Equity Incentive Plan Compensation and Bonus
Agreements With Our Named Executive Officers

-i-



Executive Change of Control and Severance Agreements
Outstanding Equity Awards at Fiscal Year-End for Fiscal 2017
Perquisites, Health, Welfare and Retirement Benefits
401(k) Plan
Equity Compensation Plans
Compensation Committee Report
RELATED PERSON TRANSACTIONS28
Related Person Transactions
Related-Person Transactions Policy
SECURITY OWNERSHIP29
OTHER MATTERS31
Section 16(a) Beneficial Ownership Reporting Compliance
Fiscal Year 2017 Annual Report
Company Website
Availability of Bylaws
PROPOSALS OF STOCKHOLDERS FOR 20192021 ANNUAL MEETING
Stockholder Proposals For Inclusion in Proxy Statement
Stockholder Proposals and Director Nominations Not for Inclusion in Proxy Statement31

i

IMMUNIC, INC.





-ii-





VITAL THERAPIES, INC.
15010 Avenue of Science, Suite 200
San Diego, California 92128
PROXY STATEMENT

For the 20182020 Annual Meeting of Stockholders
to be held on May 23, 2018
July 2, 2020

The information provided in the “Questions and Answers” format below is for your convenience only and is merely a summary of the information contained in this proxy statement. You should read the entire proxy statement carefully.

QUESTIONS AND ANSWERS
ABOUT THE PROXY MATERIALS AND ANNUAL MEETING

Why am I receiving these materials?

This proxy statement and the enclosed form of proxy are furnished in connection with the solicitation of proxies by our board of directors for use at the 20182020 annual meeting of stockholders of Vital Therapies,Immunic, Inc., a Delaware corporation, and any postponements or adjournments thereof. The annual meeting will be held on Wednesday, May 23, 2018July 2, 2020 at 8:0030 a.m., Pacific Time, Eastern time, virtually via the Internet at 12235 El Camino Real, San Diego, CA 92130.

https://web.lumiagm.com/276702602. No physical meeting will be held.

Stockholders are invited to attend the annual meeting and are requested to vote on the items of business described in this proxy statement. The Notice of Internet Availability of Proxy Materials, or the Notice of Internet Availability, which contains instructions on how to access the proxy materials and our 2017 annual report, is being mailed on or about April 11, 2018 to all stockholders entitled to vote at the annual meeting.

What am I voting on?

You are being asked to vote on two proposals:

the election of the three nominees for Class I director named in this proxy statement to hold office until our 2021 annual meeting of stockholders and until their respective successors are duly elected and qualified; and
the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2018.

·the election of Dr. Vincent Ossipow and Mr. Jan Van den Bossche as Class III Directors to hold office until our 2023 annual meeting of stockholders and until their successors are duly elected and qualified; and

·the ratification of the appointment of Baker Tilly as our independent registered public accounting firm for our fiscal year ending December 31, 2020.

What if other matters are properly brought before the annual meeting?

As of the date of this proxy statement, we are not aware of any other matters that will be presented for consideration at the annual meeting. If any other matters are properly brought before the annual meeting, the persons named as proxies will be authorized to vote or otherwise act on those matters in accordance with their judgment. If for any reason a Class I director nominee isDr. Ossipow and Mr. Van den Bossche are not available as a candidatecandidates for director, the persons named as proxy holders will vote your proxy for such other candidatecandidates as may be nominated by our board of directors.



How does the board of directors recommend that I vote?

Our board of directors recommends that you vote your shares:

FOR” each of the three nominees for Class I director named in this proxy statement; and
FOR” the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2018.

·FOR” the election of Dr. Ossipow and Mr. Van den Bossche; and

·FOR” the ratification of the appointment of Baker Tilly as our independent registered public accounting firm for our fiscal year ending December 31, 2020.

Who may vote at the annual meeting?

Only stockholders of record as of the close of business on March 29, 2018,April 15, 2020, the record date, are entitled to vote at the annual meeting. As of the record date, there were 42,368,86410,823,951 shares of our common stock issued and outstanding, held by 6936 holders of record. We do not have cumulative voting rights for the election of directors.

Stockholder of Record: Record:Shares Registered in Your Name. If, at the close of business on the record date for the annual meeting, your shares were registered directly in your name with our transfer agent, American Stock Transfer & Trust Company, LLC, then you are a stockholder of record. As a stockholder of record, you have the right to grant your voting proxy directly to the individuals listed on the proxy card or to vote in personelectronically at the annual meeting.

Beneficial Owner: Shares Registered in the Name of a Broker, Bank, or Other Nominee. If, at the close of business on the record date for the annual meeting, your shares were held, not in your name, but rather in an account at a brokerage firm, bank, or other nominee, then you are the beneficial owner of shares held in “street name” and these proxy materials are being forwarded to you by that organization. The organization holding your account is considered the stockholder of record for purposes of voting at the annual meeting. As a beneficial owner, you have the right to direct your broker, bank or other nominee regarding how to vote the shares in your account by following the voting instructions your broker, bank or other nominee provides. You are also invited to attend the annual meeting. However, since you are not the stockholder of record, you may not vote your shares in personelectronically at the annual meeting unless you obtain a valid proxy from your broker, bank or other nominee.


How can I attend the annual meeting?

You may attend the annual meeting online, including to vote and/or submit questions during the meeting, by logging in at https://web.lumiagm.com/276702602. The virtual annual meeting will begin at approximately 8:30 a.m. Eastern time, with log-in beginning at approximately 8:15 a.m. on July 2, 2020. To participate in the virtual annual meeting, you will need the 16-digit control number included on your notice, on your proxy card or on the instructions that accompanied your proxy materials. Shares held in your name as the stockholder of record may be voted electronically during the annual meeting. Shares for which you are the beneficial owner but not the stockholder of record may also be voted electronically during the annual meeting. However, even if you plan to attend the virtual annual meeting, the Company recommends that you vote your shares in advance, so that your vote will be counted if you later decide not to attend the annual meeting.

How can I vote my shares?

Stockholder of Record: Shares Registered in Your Name

If you are a stockholder of record, you may vote in one of the following ways:

You may vote in person. If you plan to attend the annual meeting, you may vote by delivering your completed proxy card in person or by completing and submitting a ballot, which will be provided at the annual meeting.
You may vote by mail. Complete, sign and date the proxy card that accompanies this proxy statement and return it promptly in the postage-prepaid envelope provided (if you received printed proxy materials). Your completed, signed and dated proxy card must be received prior to the annual meeting.


You may vote by telephone. To vote over the telephone, dial toll-free 1-800-579-1639 using a touch-tone telephone and follow the recorded instructions (have your Notice of Internet Availability or proxy card in hand when you call). You will be asked to provide the company number and control number from your Notice of Internet Availability or proxy card. Telephone voting is available 24 hours a day, 7 days a week, until 11:59 p.m., Eastern Time, on May 22, 2018.
You may vote via the Internet. To vote via the Internet, go to www.proxyvote.com to complete an electronic proxy card (have your Notice of Internet Availability or proxy card in hand when you visit the website). You will be asked to provide the company number and control number from your Notice of Internet Availability or proxy card. Internet voting is available 24 hours a day, 7 days a week, until 11:59 p.m., Eastern Time, on May 22, 2018.

·You may vote electronically at the annual meeting. See above in “How can I attend the annual meeting?”

·You may vote by telephone. To vote over the telephone, dial toll-free 1 (800) 776-9437 using a touch-tone telephone and follow the recorded instructions. Have your proxy card in hand when you call. You will be asked to provide the company number and control number from your proxy card. Telephone voting is available 24 hours a day, 7 days a week, until 11:59 p.m. Eastern time, on July 1, 2020.

·You may vote via the Internet. To vote via the Internet, go to www.voteproxy.com to complete an electronic proxy card. Have your proxy card in hand when you visit the website. You will be asked to provide the company number and control number from your proxy card. Internet voting is available 24 hours a day, 7 days a week, until 11:59 p.m. Eastern time, on July 1, 2020.

Beneficial Owner: Shares Registered in the Name of a Broker, Bank or Other Nominee

If you are a beneficial owner of shares held of record by a broker, bank or other nominee, you will receive voting instructions from your broker, bank or other nominee. You must follow the voting instructions provided by your broker, bank or other nominee in order to instruct your broker, bank or other nominee on how to vote your shares. Beneficial owners of shares should generally be able to vote by returning the voting instruction card, or by telephone or via the Internet. However, the availability of telephone or Internet voting will depend on the voting process of your broker, bank, or other nominee.As discussed above, if you are a beneficial owner, you may not vote your shares in personelectronically at the annual meeting unless you obtain a legal proxy from your broker, bank or other nominee.

Can I change my vote or revoke my proxy?

Stockholder of Record: Shares Registered in Your Name. Name.

If you are a stockholder of record, you can change your vote or revoke your proxy at any time before the annual meeting by:

entering a new vote by Internet or telephone (until the applicable deadline for each method as set forth above);
returning a later-dated proxy card (which automatically revokes the earlier proxy);
providing a written notice of revocation to our corporate secretary at Vital Therapies, Inc., 15010 Avenue of Science, Suite 200, San Diego, California 92128, Attn: Corporate Secretary; or
attending the annual meeting and voting in person. Attendance at the annual meeting will not cause your previously granted proxy to be revoked unless you specifically so request.

·entering a new vote by Internet or telephone (until the applicable deadline for each method as set forth above);

·returning a later-dated proxy card (which automatically revokes the earlier proxy);

·providing a written notice of revocation to our corporate secretary at Immunic, Inc., 1200 Avenue of the Americas, Suite 200, New York, New York 10036, Attn: Corporate Secretary; or

·attending the annual meeting and voting electronically. Attendance at the annual meeting will not cause your previously granted proxy to be revoked unless you specifically so request.

Beneficial Owner: Shares Registered in the Name of a Broker, Bank or Other Nominee. Nominee. If you are the beneficial owner of your shares, you must contact the broker, bank or other nominee holding your shares and follow their instructions to change your vote or revoke your proxy.

Why did I receive a notice in the mail regarding the Internet availability of the proxy materials instead of a paper copy of the full set of proxy materials?



In accordance with the rules of the Securities and Exchange Commission, or SEC, we have elected to distribute our proxy materials, including the notice of annual meeting of stockholders, this proxy statement and our 2017 annual report, primarily via the Internet. As a result, we are mailing to many of our stockholders a Notice of Internet Availability instead of a paper copy of the proxy materials. The Notice of Internet Availability contains instructions on how to access our proxy materials on the Internet, how to vote at the annual meeting, and how to request printed copies of the proxy materials and the 2017 annual report. We encourage stockholders to take advantage of the availability of the proxy materials on the Internet to help reduce our costs and the environmental impact of our annual meetings.

What is the effect of giving a proxy?

Proxies are solicited by, and on behalf of, our board of directors. The persons named in the proxy, Russell J. Cox,Dr. Daniel Vitt, our Chief Executive Officer, and Faheem Hasnain,Dr. Duane Nash, our Executive Chairman and Lead Director,of the Board of Directors, have been designated as proxies for the annual meeting by our board of directors. When proxies are properly dated, executed and returned, the shares represented by such proxies will be voted at the annual meeting in accordance with the instruction of the stockholder. If no specific instructions are given, however, the shares will be voted in accordance with the recommendations of our board of directors as described above and, if any other matters are properly brought before the annual meeting, the shares will be voted in accordance with the proxies’ judgment.

How many votes do I have?

On each matter to be voted upon at the annual meeting, each stockholder will be entitled to one vote for each share of our common stock held by them on the record date.

What is the quorum requirement for the annual meeting?

A quorum is the minimum number of shares required to be present or represented at the annual meeting for the meeting to be properly held under our bylaws and Delaware law. Holders of a majority of the voting power of our outstanding common stock entitled to vote at the annual meeting must be present in person or represented by proxy for us to hold and transact business at the annual meeting. On the record date, there were 42,368,86410,823,951 shares outstanding and entitled to vote. Thus, the holders of at least 21,184,4335,411,976 shares must be present in person or represented by proxy at the annual meeting to have a quorum.

Abstentions, “WITHHOLD” votes, and “broker non-votes” (as explained below) are counted as present and entitled to vote for purposes of determining a quorum. If there is no quorum, the meeting may be adjourned to another date by the chairman of the meeting or the holders of a majority of the voting power present in person or represented by proxy at the annual meeting and entitled to vote at the annual meeting may adjourn the meeting to another date.

thereat.

What are broker non-votes?

Broker non-votes occur when a beneficial owner of shares held in “street name” does not give instructions to the broker holding the shares as to how to vote on matters deemed “non-routine” and there“non-routine.” There is at least one “routine” matter to be voted upon at the meeting.meeting relating to the ratification of Baker Tilly as our independent auditors for the year ended December 31, 2020. Generally, if shares are held in street“street name, the beneficial owner of the shares is entitled to give voting instructions to the broker holding the shares. If the beneficial owner does not provide voting instructions, the broker can still vote the shares with respect to matters that are considered to be “routine,” but not with respect to “non-routine”“non-routine,” matters. In the event that a broker votes shares on the “routine” matters, but does not vote shares on the “non-routine” matters, those shares will be treated as broker non-votes with respect to the “non-routine”



proposals. Accordingly, if you own shares through a nominee, such as a broker or bank, please be sure to instruct your nominee how to vote to ensure that your vote is counted on each of the proposals.

What matters are considered “routine” and “non-routine”?

The ratification of the appointment of PricewaterhouseCoopers LLPBaker Tilly as our independent registered public accounting firm for our fiscal year ending December 31, 20182020 (Proposal No. 2) is considered routine under applicable federal securities rules. The election of Class I directorsIII Directors (Proposal No. 1) is considered “non-routine” under applicable federal securities rules.

What are the effects of abstentions and broker non-votes?

An abstention represents a stockholder’s affirmative choice to decline to vote on a proposal. If a stockholder indicates on its proxy card that it wishes to abstain from voting its shares, or if a broker, bank or other nominee holding its customers’ shares of record causes abstentions to be recorded for shares, these shares will be considered present and entitled to vote at the annual meeting. As a result, abstentions will be counted for purposes of determining the presence or absence of a quorum and will also count as votes against a proposal in cases where approval of the proposal requires the affirmative vote of a majority of the shares present in person or represented by proxy and entitled to vote at the annual meeting (e.g., Proposal(Proposal No. 2). However, because the outcome of Proposal No. 1 (election of directors)a director) will be determined by a plurality vote, abstentions will have no impact on the outcome of such proposal as long as a quorum exists.


Broker non-votes will be counted for purposes of calculating whether a quorum is present at the annual meeting, but will not be counted for purposes of determining the number of votes cast. Therefore, a broker non-vote will make a quorum more readily attainable but will not otherwise affect the outcome of the vote on any proposal.

What is the voting requirement to approve each of the proposals?

Proposal No. 1: Election of Class IIII Directors. The election of Class I directorsDr. Ossipow and Mr. Van den Bossche requires a plurality of the votes cast by the holders of shares present in person or represented by proxy at the annual meeting and entitled to vote on the election of directors. This means that the three nominees for Class I director receiving the highest number of “FOR” votesif Dr. Ossipow and Mr. Van den Bossche receive a single vote, they will be elected as Class I directors.III Directors. You may vote (i) “FOR” for each director nominee or (ii) “WITHHOLD” for each director nominee.Dr. Ossipow and Mr. Van den Bossche. Because the outcome of this proposal will be determined by a plurality vote, shares voted “WITHHOLD” will not prevent a director nomineeDr. Ossipow and Mr. Van den Bossche from being elected as a director.directors. Shares voted “WITHHOLD” will count towards the quorum requirement for the annual meeting.

Proposal No. 2: Ratification of Appointment of PricewaterhouseCoopers LLPBaker Tilly. The ratification of the appointment of PricewaterhouseCoopers LLPBaker Tilly requires the affirmative vote of a majority of the shares present in person or represented by proxy at the annual meeting and entitled to vote thereon to be approved. You may vote “FOR,” “AGAINST,” or “ABSTAIN” on this proposal. Abstentions will count towards the quorum requirement for the annual meeting and will have the same effect as a vote against the proposal.

Who will count the votes?

A representative of Broadridge Financial Solutions, Inc.American Stock Transfer & Trust Company, LLC will tabulate the votes and act as inspector of elections.



What if I do not specify how my shares are to be voted or fail to provide timely directions to my broker, bank or other nominee?

Stockholder of Record: Shares Registered in Your Name. If you are a stockholder of record and you submit a proxy but you do not provide voting instructions, your shares will be voted:

FOR” each of the three nominees for Class I director named in this proxy statement; and
FOR” the ratification of the appointment of PricewaterhouseCoopers LLP as our independent registered public accounting firm for our fiscal year ending December 31, 2018.

·FOR” the election of Dr. Ossipow and Mr. Van den Bossche; and

·FOR” the ratification of the appointment of Baker Tilly as our independent registered public accounting firm for our fiscal year ending December 31, 2020.

In addition, if any other matters are properly brought before the annual meeting, the persons named as proxies will be authorized to vote or otherwise act on those matters in accordance with their judgment.

Beneficial Owner: Shares Registered in the Name of a Broker, Bank or Other Nominee. Brokers, banks and other nominees holding shares of common stock in street name“street name” for customers are generally required to vote such shares in the manner directed by their customers. In the absence of timely directions, your broker, bank or other nominee will have discretion to vote your shares on our sole “routine” matter - Proposal No. 2 relating to ratifyratifying the appointment of PricewaterhouseCoopers LLP.Baker Tilly. Absent direction from you, however, your broker, bank or other nominee will not have the discretion to vote on Proposal No. 1 relating to the election of directors.

a director.

How can I contact Vital Therapies’Immunic’s transfer agent?

You may contact our transfer agent by writing American Stock Transfer & Trust Company, LLC, 6201 15th Avenue, Brooklyn, New York 11219. You may also contact our transfer agent via email at help@astfinancial.com or by telephone at 1 (800) 937-5449.

How can I attend the annual meeting?
Stockholder of Record: Shares Registered in Your Name. If you were a stockholder of record at the close of business on the record date, you must present valid government-issued photo identification (e.g., driver’s license or passport) for admission to the annual meeting.
Beneficial Owners: Shares Registered in the Name of a Broker, Bank or Other Nominee. If you were a beneficial owner at the close of business on the record date, you may not vote your shares in person at the annual meeting unless you obtain a “legal proxy” from your broker, bank or other nominee who is the stockholder of record with respect to your shares. You may still attend the annual meeting even if you do not have a legal proxy. For admission to the annual meeting, you must provide proof of beneficial ownership as of the record date (e.g., your most recent account statement reflecting your stock ownership as of the record date) and you must present valid government-issued photo identification.
Please allow ample time for check-in. Please note that cameras, recording equipment, large bags, briefcases or packages will not be permitted in the annual meeting.


Will the annual meeting be webcast?
We do not expect to webcast the annual meeting.

How are proxies solicited for the annual meeting, and who is paying for such solicitation?

This year we are furnishing our proxy materials to our stockholders primarily via “Notice and Access” delivery pursuant to Securities and Exchange Commission (“SEC”) rules. On May 4, 2020, we mailed to our stockholders a “Notice Regarding the Availability of Proxy Materials” (the “Notice”) containing instructions on how to access the proxy materials via the Internet. Utilizing this method of proxy delivery expedites receipt of proxy materials by our stockholders, reduces the cost of producing and mailing the full set of proxy materials and helps us contribute to sustainable practices.

If you receive a Notice by mail, you will not receive a printed copy of the proxy materials in the mail. Instead, the Notice instructs you on how to access the proxy materials and vote over the Internet. If you received a Notice by mail and would like to receive paper copies of our proxy materials in the mail, you may follow the instructions in the Notice for making this request. The Notice also contains instructions on how you may request to receive an electronic copy of our proxy materials by email.


Our board of directors is soliciting proxies for use at the annual meeting by means of the proxy materials. We will bear the entire cost of proxy solicitation, including the preparation, assembly, printing, mailing and distribution of the proxy materials. Copies of solicitation materials will also be made available upon request to brokers, banks and other nominees to forward to the beneficial owners of the shares held of record by such brokers, banks or other nominees.solicitation. The original solicitation of proxies may be supplemented by solicitation by telephone, electronic communication, or other means by our directors, officers or employees. No additional compensation will be paid to these individuals for any such services, although we may reimburse such individuals for their reasonable out-of-pocket expenses in connection with such solicitation. We do not plan to retain a proxy solicitor to assist in the solicitation of proxies.

If you choose to access the proxy materials and/or vote over the Internet, you are responsible for any Internet access charges you may incur. If you choose to vote by telephone, you are responsible for any telephone charges you may incur.

Where can I find the voting results of the annual meeting?

We will announce preliminary voting results at the annual meeting. We will also disclose voting results on a Current Report on Form 8-K filed with the SEC within four business days after the annual meeting. If final voting results are not available to us in time to file a Current Report on Form 8-K within four business days after the annual meeting, we will file a Current Report on Form 8-K to publish preliminary results and, within four business days after final results are known, file an additional Current Report on Form 8-K to publish the final results.

What does it mean if I receive more than one Notice of Internet Availability or more than one set of printed materials?

If you receive more than one Notice of Internet Availability or more than one set of printed materials, your shares may be registered in more than one name and/or are registered in different accounts. Please follow the voting instructions on each Notice of Internet Availability or each set of printed materials as applicable, to ensure that all of your shares are voted.

I share an address with another stockholder, and we received only one printed copy of the proxy materials. How may I obtain an additional copy of the proxy materials?

We have adopted an SEC-approved procedure called “householding,” under which we can deliver a single copy of the proxy materials and annual report to multiple stockholders who share the same address unless we receive contrary instructions from one or more of the stockholders. This procedure reduces our printing and mailing costs. Stockholders who participate in householding will continue to be able to access and receive separate proxy cards. Upon written or oral request, we will undertake to promptly deliver a separate copy of the proxy materials and annual report to any stockholder at a shared address to which we delivered a single copy of any of these documents.address. To receive a separate copy, or, if you are receiving multiple copies, to request that we only send a single copy of next year’s proxy materials, and annual report, you may contact us as follows:

Immunic, Inc.


Vital Therapies, Inc.
Attention: Investor Relations
15010
1200 Avenue of Science,the Americas, Suite 200
San Diego, CA 92128

New York, New York 10036
(858) 673-6840

Stockholders who hold shares in street name“street name” may contact their brokerage firm, bank, broker-dealer or other nominee to request information about householding.

Is there a list of stockholders entitled to vote at the annual meeting?

The names of stockholders of record entitled to vote at the annual meeting will be available at the annual meeting and from our corporate secretary for ten days prior to the meeting for any purpose germane to the meeting, between the hours of 9:00 a.m. and 4:30 p.m., Pacific Time, Eastern time, at our corporate headquarters located at 150101200 Avenue of Science,the Americas, Suite 200, San Diego, California 92128.

New York, New York 10036.

When are stockholder proposals due for next year’s annual meeting?

Please see the section entitledProposals of Stockholders for 20192021 Annual Meeting in this proxy statement for more information regarding the deadlines for the submission of stockholder proposals for our 20192021 annual meeting.

What are the implications of being an “emerging growth company”?


We are an “emerging growth company” under applicable federal securities laws and therefore are permitted to take advantage of certain reduced public company reporting requirements. As an emerging growth company, we provide in this proxy statement the scaled disclosure permitted under the Jumpstart Our Business Startups Act of 2012, or the JOBS Act, including certain executive compensation disclosures required of a “smaller reporting company,” as that term is defined in Rule 12b-2 promulgated under the Securities Exchange Act of 1934, as amended, or the Exchange Act. In addition, as an emerging growth company, we are not required to conduct votes seeking approval, on an advisory basis, of the compensation of our named executive officers or the frequency with which such votes must be conducted. We will remain an “emerging growth company” until as late as December 31, 2019 (the fiscal year-end following the fifth anniversary of the completion of our initial public offering), though we may cease to be an “emerging growth company” earlier under certain circumstances, including (i) if our gross revenue exceeds $1.07 billion in any fiscal year, or (ii) if the market value of our common stock that is held by non-affiliates exceeds $700 million as of any June 30, in which case we would cease to be an “emerging growth company” as of the following December 31.




BOARD OF DIRECTORS AND CORPORATE GOVERNANCE


Composition of the Board

Our board of directors or board,(“board”) is currently composed of elevenseven members. Philip M. Croxford, who has servedWith the exception of Dr. Nash, Mr. Phillips and Ms. Howson, all of our current directors began their service in April 2019 in connection with the stock-for-stock exchange transaction between the Company (then known as a director since 2009,Vital Therapies, Inc.) and Randolph C. Steer, M.D., Ph.D., who has served as a director since 2005, are not seeking reelection to the board and their terms as directors will expire at the annual meeting. The board would like to thank Mr. Croxford and Dr. Steer for their dedicated service to Vital Therapies. Although we presently have eleven directors, as a result of Mr. Croxford and Dr. Steer’s departures from the board, the board is reducing the number of directors from eleven to nine and has rebalanced the classificationImmunic AG (the “Exchange Transaction”). Five of the remaining directors. Mr. Croxford and Dr. Steer will continue to serve until their terms expire at the annual meeting, at which time the reduction to nine directors will take effect, and Mr. Bienaimé and Mr. Halperin are moving to Class I from Classes II and III, respectively.  Thus, the board is nominating three Class I nominees for election. Ten of the elevenseven directors that currently comprise our board of directors are “independent directors” within the meaning of such term as set forth in the listing standards of the Nasdaq Stock Market, LLC or Nasdaq.(“Nasdaq”). Our board of directors is divided into three staggered classes of directors. At each annual meeting of stockholders, a class of directors will be elected for a term of three years to succeed the class of directors whose terms are then expiring.

The following table sets forth the names, ages, and certain other information for each of the directorsdirector with termsa term expiring at the annual meeting (who areis also nomineesa nominee for election as a director at the annual meeting) and for each of the continuing members of our board of directors.board. All information is as of March 29, 2018.


Name Class Age Position Director
Since
 Current
Term
Expires
 Expiration of
Term for Which
Nominated

Nominees for Director            
Jean-Jacques Bienaimé (1) I 64 Director 2013 2018 2021
Russell J. Cox.

 I 54 Director and Chief Executive Officer 2018 2018 2021
Errol R. Halperin (2)(3) I 77 Director 2012 2018 2021
Continuing Directors            
Faheem Hasnain (1) II 59 Chairman 2016 2019 
Douglas E. Godshall (3) II 53 Director 2013 2019 
Muneer A. Satter (1)(2) II 57 Director 2013 2019 
Cheryl L. Cohen (1)(4) III 52 Director 2015 2020 
J. Michael Millis, M.D. (2)(4) III 59 Director 2006 2020 
Lowell E. Sears (2)(3) III 67 Director 2013 2020 
(1)Member of compensation committee. Ms. Cohen will become a member and chair of the compensation committee after the 2018 Annual Meeting.
(2)Member of nominating and governance committee.
(3)Member of audit committee.
(4)Member of quality and technology committee.



April 15, 2020.

Name Class Age Position Director
Since
 Current
Term
Expires
 Expiration of
Term for Which
Nominated
Nominees for Director            
Dr. Vincent Ossipow III 51 Director 2019 2020 2023
Mr. Jan Van den Bossche III 42 Director 2019 2020 2023
Continuing Directors            
Dr. Daniel Vitt I 51 Director, Chief Executive Officer, President 2019 2021 -
Dr. Duane Nash I 49 Executive Chairman of the Board 2019 2021 -
Dr. Jörg Neermann II 53 Director 2019 2022 -
Mr. Barclay Phillips II 58 Director 2019 2022 -
Ms. Tamar Howson II 71 Director 2019 2022  

Nominees for Director

Jean-Jacques Bienaimé

Dr. Vincent Ossipow. Dr. Vincent has been a member of the Board since April 2019. Dr. Ossipow is a Partner at Omega Funds. Dr. Ossipow joined Omega Funds, which manages Immunic’s current shareholder, Global Life Bioventure V S.à r.l., M.B.A. has servedin 2014 and subsequently joined NeoMed in 2017. Previously, Dr. Ossipow worked with Sectoral Asset Management, a healthcare institutional investor, as a partner for private investments. From 2000 to 2006 he was a research fellow at the University of Geneva, studying the molecular basis of brain function, and acted as Sectoral Asset Management’s Chief Scientific Officer during this period. Previously, he worked at Pictet Bank as a research analyst for biotechnology equities and as a co-manager of the Pictet Biotech Fund, a biotech-equities listed investment vehicle. Dr. Ossipow trained as a postdoctoral fellow in Geneva (Hoffman-La-Roche and Human Frontier Science Program fellow) and at the National Cancer Institute in Bethesda, MD. He completed a Certificate in International Finance and Global Markets at the Georgetown University School of Business and holds an M.S. in computational sciences, an M.S. in molecular biology, and a Ph.D. in molecular biology, all from the University of Geneva. Dr. Ossipow holds a CFA designation (Chartered Financial Analyst) from the CFA Institute. We believe that Dr. Ossipow’s extensive experience as a biotechnology investor and analyst, along with his financial and commercial expertise in the biotechnology industry, enable him to contribute important insights to our board on strategic leadership and financial matters and qualify him to serve on our boardboard.

Jan Van den Bossche. Mr. Van den Bossche has been a member of directorsthe Board since September 2013. Since May 2005,April 2019. Mr. BienaiméVan den Bossche is a partner at Immunic’s current shareholder, Fund+ N.V. He holds a master’s degree in applied economic sciences from the KULeuven, Belgium. He worked for more than 12 years as a biotech analyst at Petercam. He was involved in several public and private transactions of Belgian and Dutch Biotech companies, such as ThromoboGenics, Tigenix, UCB, AMT (Uniqure), IBA, MDxHealth. Before Mr. Van den Bossche joined Fund+, he was part of the investor relations team at the Dutch life sciences and materials sciences company DSM for more than two years. We believe that Mr. Van den Bossche’s past experience as a biotech analyst and his experience with public and private transactions qualify him to serve as a member of our board.


Continuing Directors

Dr. Duane Nash. Dr. Nash has been a member of the Board since January 2019 and has served as Chairman of the chief executive officerBoard of Directors since April 2019, and as Executive Chairman since April 2020. Dr. Nash joined the Company in 2012, prior to the Exchange Transaction and has held various leadership roles in the Company, including Medical Director, Executive Vice President, Chief Business Officer, President, and Chief Executive Officer, a director of BioMarin Pharmaceuticalposition he held until April 2019. Prior to joining the Company, Dr. Nash held various positions at Wedbush PacGrow Life Sciences, an investment bank, where he was employed from March 2009 to March 2012, serving most recently as Senior Vice President in Equity Research. Before that, he was a research analyst at Pacific Growth Equities, an investment bank, from April 2008 through March 2009, which was subsequently acquired by Wedbush Securities, Inc., a publicly-traded company that develops and commercializes innovative pharmaceuticals for serious diseases and medical conditions and, since June 2015, he has served Dr. Nash also practiced as chairman of its board. Froman attorney from November 2002 to April 2005, Mr. Bienaimé served as chairman, chief executive officer and presidentFebruary 2008, most recently at the law firm of Genencor, a biotechnology companyDavis Polk, where he focused on industrial bioproductsintellectual property litigation and targeted cancer biotherapeutics. Prior to joining Genencor, Mr. Bienaimé was chairman, president and chief executive officer of SangStat Medical Corporation, another biotechnology company. He became president of SangStat Medical Corporation, a global pharmaceutical company, in 1998 and chief executive officer in 1999. Prior to joining SangStat Medical Corporation, Mr. Bienaimé held various management positions from 1992 to 1998 with Rhône-Poulenc Rorer Pharmaceuticals (now known as Sanofi-Aventis), including Senior Vice President of Corporate Marketing and Business Development, and Vice President and General Manager of the Advanced Therapeutic and Oncology division. Mr. Bienaimé hascorporate matters. Dr. Nash served on the board of BioMarindirectors of Aerpio Pharmaceuticals, Inc. (Nasdaq: ARPO), from 2012 to 2017, and Akebia Therapeutics (Nasdaq: AKBA) from 2013 to 2018. Dr. Nash earned a B.A. in biology from Williams College, an M.D. from Dartmouth Medical School, a J.D. from the University of California, Berkeley, and an M.B.A. from the University of Oxford. Dr. Nash completed his internship in general surgery at the University of California at San Francisco. We believe that Dr. Nash’s expertise and experience as a director and his service in various executive capacities for the Company, along with his extensive experience as an executive, research analyst and attorney, qualify him to serve as a member of our board.

Tamar Howson. Ms. Howson has been a member of the Board since May 2005,October 2019. Ms. Howson is currently an Independent Director at MEI Pharma, Inc., and, the board of Incyte Corporation,until recently, was an Independent Director at Organovo Holdings, Inc. and Scientus Pharma. Earlier, she was a publicly-traded biopharmaceutical company, since January 2015. In addition, he servesSenior Advisor on the boardstransaction team at JSB-Partners, providing business development support to life sciences companies. Before that, she served as Executive Vice President, Corporate Business Development at Lexicon Pharmaceuticals, Inc. Prior, Ms. Howson was Senior Vice President, Corporate and Business Development at Bristol-Myers Squibb Company, responsible for worldwide oversight and management of the Biotech Industry Organizationidentification, evaluation and negotiation of mergers and acquisitions, licensing and other external alliance activities. Additionally, Ms. Howson spent nearly a decade at SmithKline Beecham, where she served as Senior Vice President and Director, Business Development and managed the Pharmaceutical Researchcompany’s USD 100 million venture capital fund, SR One. We believe that Ms. Howson’s extensive experience in corporate and Manufacturersbusiness development in the biotechnology and pharmaceutical industries qualify her to serve as a member of America. Mr. Bienaiméour board.

Dr. Jörg Neermann. Dr. Neermann has been a member of the Board since April 2019. Dr. Neermann works for Life Sciences Partners (“LSP”) and is the managing director of LSP Services Deutschland GmbH, which provides management services for LSP V Coöperatieve U.A., one of the Company’s stockholders. He joined LSP in 2007. Dr. Neermann’s prime focus and responsibility within LSP is to invest in unlisted securities. Prior to joining LSP, Dr. Neermann was the managing director of Deutsche Venture Capital, a venture capital and private equity division of Deutsche Bank, where he ran its healthcare investment franchise. Previously, he worked at Atlas Ventures in Germany where he also invested in the healthcare sector. Dr. Neermann has a strong scientific background and hands-on finance and investment expertise and has served on the boards of Intermune, Inc.,numerous European biotech and life science companies. Dr. Neermann is currently a publicly-traded biotechnologydirector at Probiodrug, a German biotech company from March 2012 until its acquisition by Roche Holdings, Inc.that went public on Euronext Amsterdam in September 2014 and Portola Pharmaceuticals, Inc.,is active in the development of novel, disease-modifying therapeutics against Alzheimer’s disease. Dr. Neermann studied biotechnology at the Technical University of Brunswick, Germany, and MIT in Cambridge, USA, and holds a publicly-traded biopharmaceutical company, from September 2010 through June 2014. Mr. Bienaimé earned an M.B.A.Master’s degree and a Ph.D. in biotechnology from the Wharton SchoolTechnical University in Brunswick, Germany. He also studied economics at the Technical University of Pennsylvaniain Brunswick, Germany, and a B.S. in economics from the Ecole Superieure de Commerce de Paris.

Harvard Business School. We believe that Mr. BienaiméDr. Neermann is qualified to serve on our board due to his scientific background and extensive experience as an investor in the biotechnology and healthcare industries, which enable him to contribute important insights to our board on strategic leadership and drug commercialization matters.

Dr. Daniel Vitt.Dr. Vitt is our Chief Executive Officer and a member of directorsthe board, positions he has held since April 2019. He is also managing director of Immunic Research GmbH in Halle (Saale). He joined Immunic in January 2017 from 4SC AG, a publicly listed stock company based in Martinsried, Germany, which he co-founded in 1997. At 4SC, he served as Chief Scientific Officer (CSO) and Chief Development Officer (CDO). As a member of the executive board, he was responsible for all research and development activities at 4SC group including four clinical stage products. Dr. Vitt studied chemistry in Siegen and Würzburg, Germany from 1989—1994 and graduated from the University of Würzburg. During his doctoral studies, he focused on the molecular design of small molecule therapeutics. In 1998, he received his Ph.D. from the Institute of Organic Chemistry at the University of Würzburg. We believe that Dr. Vitt’s extensive senior management experience in the management of biotechnology organizations, business development, and sales and marketing of both biotechnology and pharmaceutical products.

Russell J. Cox has servedlife sciences industry, including as the Company’s Chief Executive Officer, qualify him to serve as a member of our boardboard.


Barclay Phillips. Mr. Phillips has been a member of directorsthe Board since November 2019. Mr. Phillips is currently the Management Member of Domantle Consulting LLC, providing public and as our Chief Executive Officer since January 2018. Betweenprivate life science companies with corporate strategy, business development, communications, and financial advisory services. From 2008 to May 2014 and December 2017, he2019, Mr. Phillips served as the Executive Vice PresidentChief Financial Officer for three separate NASDAQ listed, development stage biotechnology companies; G1 Therapeutics, Inc. (GTHX), Novavax (NVAX) and Chief Operating OfficerMicromet (acquired by Amgen in 2012 for $1.2B). In addition to carrying the CFO role, Mr. Phillips also held the title of Jazz Pharmaceutical plc, or Jazz, with responsibilitySVP Corporate Development at G1 Therapeutics. During his tenure as CFO, Mr. Phillips was responsible for U.S.all finance and accounting functions, financing strategy (successfully raising over $1.4B), EUWall Street and rest-of-world commercial activities, researchinvestor relations, public relations and development, manufacturingcorporate strategy and technical operations, new product planning and global molecule leadership.corporate development. Prior to that,his CFO experience, Mr. Cox servedPhillips had extensive experience in life science venture investing and public market investing, serving for 9 years as Jazz’s Executive Vice Presidentthe Managing Director of Vector Fund Management, a late-stage life sciences venture capital fund with over $250 million in committed capital and Chief Commercial Officer from March 2012 until May 2014. Earlier, he servedapproximately 30 venture investments in biotechnology, medical technology and healthcare services companies. In addition, Mr. Phillips was Biotechnology Analyst and Director of Venture Investments for INVESCO Funds group, a variety of senior management roles at Jazz, which he joinedno-load mutual fund family with a healthcare sector fund franchise totaling over $3.5 billion in 2010. Previously,assets under management. Mr. Cox served as Senior Vice President and Chief Commercial Officer of Ipsen Group, a pharmaceutical company, from January 2009 to January 2010. From 2007 until December 2008, he was Vice President of Marketing at Tercica, Inc. prior to its acquisition by Ipsen Group. From 2003 to 2007, he served as Vice President, Marketing with Scios Inc., which was acquired by Johnson & Johnson in 2003. Before 2003, Mr. Cox spent 12 years with Genentech, Inc. where he was a Product Team Leader responsible for the Growth Hormone franchise and led numerous product launches as a Group Product Manager. Mr. CoxPhillips has served on the boardboards of directorsseveral public and private companies, including roles as Audit Chair and Chair of Aeglea BioTherapeutics, Inc., a biotechnology company, since 2015. Mr. Coxthe Nominating and Corporate Governance committees. He received a B.S.Bachelor of Arts degree in Biomedical Scienceeconomics from Texas A&M University.


the University of Colorado at Boulder. We believe that Mr. Cox is qualified to serve on our board of directors based on his extensive industry experience with life sciences companies.
Errol R. Halperin, J.D., L.L.M. has served on our board of directors since December 2012. Mr. Halperin was a senior partner of DLA Piper from January 1979 until December 2013. At the present

- 10-





time, Mr. Halperin is a senior strategic advisor to DLA Piper (U.S.). In his practice, Mr. Halperin provided general business advice to clients in a broad range of sectors, including the manufacturing, real estate industry and the real estate investment trust industry. Mr. Halperin’s practice was concentratedPhillips’ significant expertise in the areas of mergersfinancing strategy, capital markets, and acquisitions, corporate law, international transactions, real estate law and federal income tax law. Mr. Halperin has also served on the board of Equity Residential, a public REIT, and private company boards. Currently, he is a director of Elkay Manufacturing Company, a privately held corporation, and Pangea Properties, a private real estate investment and management company. He also currently serves as a director of other late stage private venturebusiness development for multiple, Nasdaq-listed life science companies including LINQ3, LLC and Restorsea, LLC. Before joining DLA Piper, from June 1972qualify him to January 1979 he was legislation counsel of the Joint Committee on Taxation of the U.S. Congress; and was an assistant branch chief of the Legislation and Regulations Division of the Chief Counsel for the Internal Revenue Service from June 1968 to June 1972. Mr. Halperin earned a B.S. and a J.D. from DePaul University and an L.L.M. in taxation from New York University.
We believe that Mr. Halperin is qualified to serve on our board of directors based on his experience as an attorney practicing for a nationally known firm in the areas of mergers and acquisitions and corporate transactions and his involvement in advising venture capital backed companies.

Continuing Directors

Faheem Hasnain has served on our board of directors since August 2016 and as Chairman and Lead Director since September 2017. Mr. Hasnain is currently Chairman and Chief Executive Officer of Gossamer Bio, Inc., a newly-formed company focused on the discovery and development of novel and differentiated therapeutic products to address unmet need amongst various targeted patient populations. Previously, Mr. Hasnain served as the Chief Executive Officer, President, and a director at Receptos, Inc. from November 2010 to August 2015, when the company was acquired by Celgene Corporation. Prior to joining Receptos, Inc., Mr. Hasnain was the President and Chief Executive Officer and a director of Facet Biotech Corporation, a biology-driven antibody company with a focus in multiple sclerosis and oncology. He held that position from December 2008 until the company’s acquisition by Abbott Laboratories in April 2010. Previously, Mr. Hasnain was President, Chief Executive Officer and a director of PDL BioPharma, Inc. from October 2008 until Facet Biotech was spun off from PDL BioPharma in December 2008. From October 2004 to September 2008, Mr. Hasnain was at Biogen Inc., most recently as Executive Vice President in charge of the oncology/rheumatology strategic business unit. Prior to Biogen, Mr. Hasnain held roles with Bristol Myers Squibb, where he was President of the Oncology Therapeutics Network, and for 14 years at GlaxoSmithKline and its predecessor organizations. He has been Chairman of the Board of Sente, Inc. since 2008 and of Tocagen Inc. since November 2014, and has served as a member of the board of directors of Kura Oncology, Inc. since April 2015. He previously served as a member of the board of directors of Ambit Biosciences Corporation, Seragon Pharmaceuticals, Tercica, Inc., Aragon Pharmaceuticals and Somaxon Pharmaceuticals, Inc. Mr. Hasnain received a B.H.K. and B.Ed. from the University of Windsor Ontario in Canada.
We believe that Mr. Hasnain is qualified to serve on our board of directors based on his extensive operational and leadership experience in biotechnology and pharmaceutical companies and as a director of publicly-traded companies.
We believe that Mr. Godshall is qualified to serve on our board of directors based on his experience as an executive officer and director of several life sciences and medical technology companies.

- 11-





Douglas E. Godshall, M.B.A. has served on our board of directors since May 2013. Mr. Godshall is currently Chief Executive Officer of Shockwave Medical Inc., a private company that develops and commercializes interventional devices utilizing lithotripsy technology for the treatment of complex vascular calcification. Previously, hewas the Chief Executive Officer of HeartWare International, Inc., a developer of a range of implantable mechanical circulatory assist devices, starting in September 2006 and a director since October 2006, until the company was acquired by Medtronic in August 2016. Prior to joining HeartWare, Mr. Godshall served in various executive and managerial positions at Boston Scientific Corporation, a manufacturer and a developer of medical supplies and medical devices in a variety of fields, including as a member of Boston Scientific’s Operating Committee and President, Vascular Surgery. Previously, Mr. Godshall had spent five years as Vice President, Business Development, at Boston Scientific, where he was focused on acquisition strategies for the cardiology, electrophysiology, neuroradiology and vascular surgery divisions. In March 2012, Mr. Godshall was appointed a director of pSivida Corp., a developer of drug delivery products for treatment of back-of-the-eye diseases. Mr. Godshall earned a B.A. in business from Lafayette College and an M.B.A from Northeastern University.
Muneer A. Satter, J.D., M.B.A. is a director of Vital Therapies and served as a co-Chairman of Vital Therapies’ Board of Directors from 2012 to September 2017. Mr. Satter has been Founder and Managing Partner of Satter Medical Technology Partners, L.P. since 2016, Chairman of Satter Investment Management LLC since 2012, and he also manages the Satter Foundation. Previously, Mr. Satter was a partner at Goldman Sachs where he spent 24 years in various roles, most recently as the Global Head of the Mezzanine Group in the Merchant Banking Division, where he raised and managed over $30 billion of assets. Mr. Satter is chairman of the board of directors of Akebia Therapeutics, Inc., Aerpio Therapeutics and Restorsea Holdings, LLC, and a director of Linq3 Technologies LLC and Annexon Biosciences. He also serves as vice chairman of the Goldman Sachs Foundation and GS Gives, is a director of the Navy SEAL Foundation, a director of World Business Chicago, is on the Board of Advisors of the American Enterprise Institute and is on the Board of Trustees of Northwestern University where he is Chairman of the Finance Committee. Mr. Satter received a B.A. in Economics from Northwestern University, a J.D. from Harvard Law School and an M.B.A. from Harvard Business School.
We believe Mr. Satter is qualified to serve on our board of directors because of his extensive experience in merchant banking and venture capital investments and his experience as an investor and director of other companies in the life sciences and medical technology industries.
Cheryl L. Cohen has served on our board of directors since July 2015. Ms. Cohen served as chief commercial officer of Medivation, Inc., a publicly-traded bio-pharmaceutical company, from September 2011 until July 2014. Ms. Cohen currently serves as president of CLC Consulting, a pharmaceutical and biotechnology consulting firm specializing in new product start-up and commercialization, where she also served as president from September 2008 until September 2011. From November 2007 to September 2008, she served as the vice president, strategic commercial group, of Health Care Systems, Inc., a Johnson & Johnson company, and from October 1998 to November 2007, she worked at Janssen Biotech, Inc. (formerly Centocor Biotech, Inc.), a Johnson & Johnson company, in a variety of senior sales roles including vice president, rheumatology franchise. Ms. Cohen has served on the board of Novus Pharmaceuticals, Inc. (reverse merger of Tokai Pharmaceuticals, Inc.), a publicly-traded pharmaceutical company focused on the acquisition, development, and commercialization of ear, nose, and throat products. Ms. Cohen served on the board of Protein Sciences Corporation, a privately held bio-pharmaceutical company specializing in vaccine development from October 2014 to August 2017, and she served on the board of Cytrx Corporation, a publicly traded bio-pharmaceutical company

- 12-





specializing in oncology, from June 2015 through October 2016. Ms. Cohen began her career at Solvay Pharmaceuticals in a variety of sales positions. Ms. Cohen received her B.A. from Saint Joseph College.
We believe that Ms. Cohen is qualified to serve on our board of directors based on her experience as an executive officer and director of private and publicly-traded companies, including companies in the pharmaceutical and bio-pharmaceutical industries.
J. Michael Millis, M.D. has served on our board of directors since 2006. Dr. Millis is a Professor of Surgery and Vice Chair of Global Surgery, Director of Hepatobiliary Surgeryat the University of Chicago. Dr. Millis currently serves on the medical staff at the University of Chicago Hospital. His current research explores the application of cellular technology on patient care, including how hepatocyte transplantation, extracorporeal assist technology and stem cells can assist in the care of patients with liver disease or liver tumors. Dr. Millis has been associated with the ELAD System since 1994, and was an investigator on the Phase 1 clinical trial. He has been the chairman of the Vital Therapies Clinical Advisory Board since 2003. Dr. Millis currently serves or has served in the past on a variety of committees, such as the American Association for the Study of Liver Diseases’ Ethics Committee, the American Society of Transplant Surgeons, Studies of Pediatric Liver Transplantation Scientific Advisory Board and Publication and Research Committee, and the ROBI Liver Intestinal Subcommittee, for which he is the former chairman. Dr. Millis is also a member of the Medical Advisory Committee of the American Liver Foundation Illinois Chapter. He also serves on the board of directors of Gift of Hope (the organ procurement organization for Illinois) and the Editorial Board of the American Journal of Transplantation, Transplantation, and Liver Transplantation. He earned a B.A. in chemistry and political science from Emory University and an M.D. with high honors from the University of Tennessee. He completed his surgical residency, clinical and research fellowship in liver transplantation at the University of California, Los Angeles. He also received his M.B.A. from University of Massachusetts, Amherst in 2014.
We believe that Dr. Millis is qualified to serve on our board of directors based on his participation on multiple advisory committees and boards and his research in the treatment of liver disease.
Lowell E. Sears, M.B.A. has served on our board of directors since May 2013. Mr.  Sears is the Chairman and Chief Executive Officer of Sears Capital Management, a venture investment and portfolio management firm specializing in life sciences. From February 2012 to January 2017, he served on the board of directors of Cellerant Therapeutics, Inc., a clinical stage biotechnology company focused on the regulation of the hematopoietic, or blood-forming, system. From September 2005 to March 2017, Mr. Sears has also served on the board of directors of SymBio Pharmaceuticals, KK, Ltd., a biotechnology company that is engaged in identifying and developing therapeutics for the treatment of leukemia, multiple myeloma and lymphoma. He has served on the board of directors of SiteOne Therapeutics, Inc., a privately-held company developing small molecular pain therapies, and has been Chairman of the Board since September 2014. He has also served on the board of directors of Halcyon Medical, a cardiovascular device company, since April 2014. From 1986 until 1994, Mr. Sears was a part of the senior management team of Amgen, Inc., a developer and manufacturer of therapeutics targeting cancers, kidney ailments, inflammatory disorders, and metabolic diseases, where he was Chief Financial Officer as well as the Senior Vice President responsible for the Asia Pacific Region. Prior to joining Amgen, Mr. Sears held senior planning and financial positions with Atlantic Richfield Company, an oil company from 1976 until 1986, including Chief Financial Officer for its Ventures Division. He earned a B.A. in economics from Claremont McKenna College and an M.B.A. from the Stanford University Graduate School of Business.

- 13-





We believe that Mr. Sears is qualified to serve on our board of directors based on his experience as a senior manager and director of private and publicly-traded companies, including several in the life sciences industry.

board.

Director Independence

As a company listed on the Nasdaq Global Market we are required under the

The listing rules of Nasdaq or the Nasdaq listing rules,require us to maintain a board comprised of a majority of independent directors, as determined affirmatively by our board. In addition, the Nasdaq listing rules require that, subject to specified exceptions, each member of our audit, compensation and nominating and governance committees must be independent. Audit committee members and compensation committee members must also satisfy the independence criteria set forth in Rule 10A-3 and Rule 10C-1, respectively, under the Exchange Act. Under the Nasdaq listing rules, a director will only qualify as an “independent director” if, in the opinion of our board, of directors, the director does not have a relationship that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director.

his or her responsibilities.

Our board of directors has undertaken a review of the independence of our directors and considered whether any director has a material relationship with us that could compromise his or her ability to exercise independent judgment in carrying out his or her responsibilities. Based upon information requested from and provided by each director concerning his or her background, employment and affiliations, including family relationships, our board of directors has determined that none of Drs. MillisMs. Howson, Dr. Neermann, Dr. Ossipow, Mr. Phillips and Steer, Ms. Cohen and Messrs. Hasnain, Bienaimé, Croxford, Godshall, Halperin, Satter and Sears,Mr. Van den Bossche, representing tenfive of our elevenseven directors, has a relationship that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director and that they each of these directors isare an “independent director” as that term is defined under the Nasdaq listing rules. Dr. Winters was not considered an independent director,Nash and Mr. Cox isDr. Vitt are not currently considered an independent directordirectors because of their positions as our former and current Chief Executive Officer, respectively.

In making these determinations, our board of directors considered the relationships that each non-employee director has with us and all other facts and circumstances our board of directors deemed relevant in determining their independence, including consulting relationships, family relationships and the beneficial ownership of our capital stock by each non-employee director.


Board Leadership Structure and Lead Director

Our board of directors is currently chaired by Mr. Hasnain. Although not currently serving as such, the Senior Preferred Investors’ Rights Agreement, or the Senior Preferred IRA, provides that Mr. Satter can elect to serve as our Lead Director.

Dr. Nash. Our board of directors believes that Vital Therapiesthe Company and its stockholders are currently best served by having Mr. Hasnain serve asthis leadership structure. As Executive Chairman, of the Board. As Chairman, Mr. HasnainDr. Nash promotes unified leadership and direction for our board and management and provides the critical leadership necessary for carrying out our strategic initiatives. Mr. Hasnain,Dr. Nash, together with our board’s strong committee system and substantial majority of independent directors, allows our board to maintain effective oversight of our business operations, including independent oversight of our financial statements, executive compensation, selection of director candidates, and corporate governance programs. We believe our current board

- 14-





leadership structure enhances the board’s ability to effectively carry out its roles and responsibilities on behalf of our stockholders.


Role of Board in Risk Oversight Process

Our board has an active role, as a whole and also at the committee level, in overseeing the management of our risks.risk management. Our board is responsible for general oversight of risks and regular review of information regarding our risks,risk management, including financial, strategic, and operational risks. The compensation committee is responsible for overseeing the management of risks relating to our executive compensation plans and arrangements, and whether our compensation policies and programs have the potential to encourage excessive risk taking. The audit committee is responsible for overseeing the management of risks relating to accounting matters and financial reporting. The nominating and governance committee is responsible for overseeing our corporate governance practices and the management of risks associated with theboard independence of the board and potential conflicts of interest. Although each committee is responsible for evaluating certain risks and overseeing the management of suchcertain risks, the entire board is regularly informed through discussions from committee members about such risks. The board believes its leadership structure is consistent with and supports the administration of its risk oversight function.


Board Meetings and Committees

During

After the Exchange Transaction and during our fiscal year ended December 31, 2017,2019, our board of directors held sixfive meetings (including regularly scheduled and special meetings), and each director attended at least 75% of the aggregate of (i) the total number of meetings of our board of directors held during the period for which he or she has been a director and (ii) the total number of meetings held by all committees of our board of directors on which he or she served during the periods that he or she served.

Our board of directors has established an audit committee, a compensation committee, and a nominating and governance committee, and a quality and technology committee. The composition and responsibilities of each of the committees of our board of directors is described below.

Audit Committee

Our board of directors has a separately-designated standing audit committee, which operates pursuant to a charter.

Our audit committee members currently consist of Messrs. Godshall, HalperinMr. Phillips, Mr. Van den Bossche and Sears.Dr. Neermann. Mr. SearsPhillips serves as the chairman. Each of the members of our audit committee is an independent director under the Nasdaq listing rules, satisfies the additional independence criteria for audit committee members and satisfies the requirements for financial literacy under the Nasdaq listing rules and Rule 10A-3 of the Exchange Act, as applicable. Our board has also determined that Mr. Sears qualifiesPhillips and Mr. Van den Bossche each qualify as an audit committee financial expert within the meaning of the applicable rules and regulations of the SEC and satisfiessatisfy the financial sophistication requirements of the Nasdaq listing rules.

Our audit committee oversees our corporate accounting and financial reporting process and assists our board of directors in monitoring our financial systems and our legal and regulatory compliance. Our audit committee also:

oversees the work of our independent auditors;

- 15-





approves the hiring, discharging and compensation of our independent auditors;
approves engagements of the independent auditors to render any audit or permissible non-audit services;
reviews the qualifications, independence and performance of the independent auditors;
reviews our financial statements and our critical accounting policies and estimates;
reviews the adequacy and effectiveness of our internal controls;
reviews our policies with respect to risk assessment and risk management;
reviews and monitors our policies and procedures relating to related person transactions; and
reviews and discusses with management and the independent auditors the results of our annual audit, our quarterly financial statements and our publicly filed reports.

·oversees the work of our independent auditors;

·approves the hiring, discharging and compensation of our independent auditors;

·approves engagements of the independent auditors to render any audit or permissible non-audit services;

·reviews the qualifications, independence and performance of the independent auditors;

·reviews our financial statements and our critical accounting policies and estimates;

·reviews the adequacy and effectiveness of our internal controls;

·reviews our policies with respect to risk assessment and risk management;

·reviews and monitors our policies and procedures relating to related person transactions; and

·reviews and discusses with management and the independent auditors the results of our annual audit, our quarterly financial statements and our publicly filed reports.

Our audit committee operates under a written charter approved by our board of directors and that satisfies the applicable rules and regulations of the SEC and the listing requirements of Nasdaq. The charter is available on the corporate governance section of our website, which is located at http://ir.vitaltherapies.com/corporate-governance. Ourir.imux.com. Following the Exchange Transaction, our audit committee held sixfour meetings during 2017.

2019.

Compensation Committee

The members of our compensation committee are Messrs. Bienaimé, Hasnain and Satter,Ms. Howson and Dr. Steer. Dr. SteerNeermann. Ms. Howson is currently the chairman of our compensation committee. At the expiration of Dr. Steer’s term as director at the annual meeting, Ms. Cohen will join the compensation committee and succeed Dr. Steer as chair. Our board of directors has determined that each member of our compensation committee is an independent director under the current rules of Nasdaq, satisfies the additional independence criteria for compensation committee members under Rule 10C-1 and the Nasdaq listing rules, is a “non-employee director” within the meaning of Rule 16b-3 under the Exchange Act, and is an “outside director” for purposes of Section 162(m) of the Internal Revenue Code of 1986, as amended.


Our compensation committee oversees our corporate compensation programs. The compensation committee also:

reviews and recommends for approval by the members of our board of directors policies, plans and arrangements relating to compensation and benefits of our officers and employees;
reviews and recommends for approval by the members of our board of directors corporate goals and objectives relevant to the compensation of our Chief Executive Officer and other executive officers;
evaluates the performance of our executive officers in light of established goals and objectives;

- 16-





recommends compensation of our executive officers based on its evaluations;
reviews and discusses with management the compensation disclosures required by SEC rules;
engages a compensation consultant, legal counsel or other advisors (other than in-house legal counsel) to advise on executive compensation and assess the independence of each in accordance with Nasdaq;
evaluates whether any compensation consultant, legal counsel or other advisor (other than in-house legal counsel) has a conflict of interest in accordance with the SEC rules; and
prepares the annual compensation committee report required by SEC rules.

·reviews and recommends for board approval policies, plans and arrangements relating to compensation and benefits of our officers and employees;

·reviews and recommends for board approval corporate goals and objectives relevant to the compensation of our Chief Executive Officer and other executive officers;

·evaluates the performance of our executive officers in light of established goals and objectives;

·recommends compensation of our executive officers based on its evaluations;

·reviews and discusses with management the compensation disclosures required by SEC rules;

·engages a compensation consultant, legal counsel or other external advisors to advise on executive compensation and assess the independence of executive officers in accordance with Nasdaq;

·evaluates whether any compensation consultant, legal counsel or other external advisor has a conflict of interest in accordance with the SEC rules; and

·prepares the annual compensation committee report required by SEC rules.

Our compensation committee operates under a written charter approved by our board of directors and thatwhich satisfies the applicable rules and regulations of the SEC and the listing requirements of Nasdaq. The charter is available on our website at http://ir.vitaltherapies.com/corporate-governance. Ourir.imux.com. Following the Exchange Transaction, our compensation committee held fivefour meetings during 2017.

2019.

Nominating and Governance Committee

The members of our nominating and governance committee are Messrs. Halperin, Satter and Sears,Mr. Van den Bossche and Dr. Millis. Mr. HalperinOssipow. Dr. Ossipow is the chairman of our nominating and governance committee. Our board of directors has determined that each member of our nominating and governance committee is independent under the Nasdaq listing rules.

Our nominating and governance committee oversees and assists our board of directors in reviewing and recommending nominees for election as directors. The nominating and governance committee also:

evaluates and makes recommendations regarding the organization and governance of our board of directors and its committees;
assesses the performance of members of our board of directors and makes recommendations regarding committee and chair assignments;
recommends desired qualifications for board of director membership and conducts searches for potential members of our board of directors; and
reviews and makes recommendations with regard to our corporate governance guidelines.

·evaluates and makes recommendations regarding the organization and governance of our board and its committees;

·assesses the performance of members of our board and makes recommendations regarding committee and chair assignments;

·recommends desired qualifications for board membership and conducts searches for potential members of our board; and

·reviews and makes recommendations with regard to our corporate governance guidelines.

Our nominating and governance committee operates under a written charter approved by our board of directors and thatwhich satisfies the applicable rules and regulations of the SEC and the listing requirements of Nasdaq. The charter is available on our website at http://ir.vitaltherapies.com/corporate-governance. Ourir.imux.com. Following the Exchange Transaction, our nominating and governance committee held two meetingsone meeting during 2017.

Quality and Technology Committee

- 17-





Our quality and technology committee provides assistance to our board of directors in its oversight of product quality and safety, manufacturing practices, scientific and technical direction and human and animal studies. The members of our quality and technology committee are Ms. Cohen, Mr. Croxford and Drs. Millis and Steer. Dr. Millis is the chairman of our quality and technology committee. Our quality and technology committee operates under a written charter approved by our board of directors. The charter is available on our website at http://ir.vitaltherapies.com/corporate-governance. Our quality and technology committee held thirteen meetings during 2017.

2019.

Compensation Committee Interlocks and Insider Participation

During 2017, the members of our compensation committee were, and currently are, Messrs. Bienaimé, Hasnain, and Satter, and Dr. Steer.

None of the current or past members of our compensation committee is or has been an officer or employee of the company.Company. None of our executive officers currently serves, or in the past year has served, as a member of the compensation committee (or other board committee performing equivalent functions or, in the absence of any such committee, the entire board of directors)board) or director of any entity that has one or more executive officers serving on our compensation committee or our board of directors.


board.

Considerations in Evaluating Director Nominees

In its evaluation of director candidates, including the member or members of the board of directors eligible for reelection, our nominating and governance committee will consider the following:

·The current size and composition of our board and the needs of the board and its respective committees;


The current size and composition of our board of directors and the needs of the board and its respective committees;
Factors such as character, integrity, judgment, diversity of experience, independence, area of expertise, corporate experience, length of service, potential conflicts of interest, other commitments, and the like. Our nominating and governance committee evaluates these factors, among others, and does not assign any particular weighting or priority to any of these factors; and
Other factors that our nominating and governance committee may consider appropriate.
·Factors such as character, integrity, judgment, diversity of experience, independence, area of expertise, corporate experience, length of service, potential conflicts of interest, other commitments, and the like. Our nominating and governance committee evaluates these factors, among others, and does not assign any particular weighting or priority to any of these factors; and

·Other factors that our nominating and governance committee may consider appropriate.

The nominating and governance committee also focuses on issues of diversity, such as diversity in experience, international perspective, background, expertise, skills, age, gender, and ethnicity. The nominating and governance committee does not have a formal policy with respect to diversity; however, our board of directors and the nominating and governance committee believe that it is essential that members of our board of directors represent diverse viewpoints. Any nominee for a position on the board must satisfy the following minimum qualifications:

The highest personal and professional ethics and integrity;
Proven achievement and competence in the nominee’s field and the ability to exercise sound business judgment;

- 18-





Skills that are complementary to those of the existing board;
The ability to assist and support management and make significant contributions to the company’s success; and
An understanding of the fiduciary responsibilities required of a member of the board and the commitment of time and energy necessary to diligently carry out those responsibilities.

·The highest levels of personal and professional ethics and integrity;

·Proven achievement and competence in the nominee’s field and the ability to exercise sound business judgment;

·Skills that are complementary to those of the existing board;

·The ability to assist and support management and make significant contributions to the Company’s success; and

·An understanding of the fiduciary responsibilities required of a member of the board and the commitment of time and energy necessary to diligently carry out those responsibilities.

If our nominating and governance committee determines that an additional or replacement director is required, the committee may take such measures as it considers appropriate in connection with its evaluation of a director candidate, including candidate interviews, inquiry of the person or persons making the recommendation or nomination, engagement of an outside search firm to gather additional information, or reliance on the knowledge of the members of the committee, board or management.

After completing its review and evaluation of director candidates, our nominating and governance committee recommends to our full board of directors the director nominees for selection.nominee. Our nominating and governance committee has discretion to decide which individuals to recommend for nomination as directors and our board of directors has the final authority in determining the selection of director candidates for nomination to our board.


Requirements for Stockholder Recommendations of a Candidate to our Board

It is the policy of our nominating and governance committee to consider recommendations for candidates to our board of directors from our stockholders. A stockholder that wishes to recommend a candidate for consideration by the committee as a potential candidate for director must direct the recommendation in writing to Vital Therapies,Immunic, Inc., 150101200 Avenue of Science,the Americas, Suite 200, San Diego, California 92128,New York, New York 10036, Attention: Corporate Secretary, and must include the candidate’s name, home and business contact information, detailed biographical data, relevant qualifications, a signed letter from the candidate confirming willingness to serve, information regarding any relationships between us and the candidate and evidence of the recommending stockholder’s ownership of our stock. Such recommendation must also include a statement from the recommending stockholder in support of the candidate, particularly within the context of the criteria for board membership, including issues of character, integrity, judgment, diversity of experience, independence, area of expertise, corporate experience, potential conflicts of interest, other commitments and the like and personal references. Further details are set forth below in “Proposals of Stockholders for 2021 Annual Meeting.”

Our nominating and governance committee will consider the recommendation but will not be obligated to take any further action with respect to the recommendation.


Communications with the Board of Directors

In cases where stockholders or other interested parties wish to communicate directly with our non-management directors, messages can be sent to Vital Therapies,Immunic, Inc., Attention: Corporate Secretary, 150101200 Avenue of Science,the Americas, Suite 200, San Diego, California 92128.New York, New York 10036. Our corporate secretary monitors these communications and will provide a summary of all received messages to the board at each regularly scheduled meeting of the board. Our board generally meets on a quarterly basis. Where the nature of a communication warrants, our corporate secretary may determine, in his or her judgment, to obtain the more


- 19-





immediate attention of the appropriate committee of the board, or non-management director, ofdirectors, independent advisors or of our management, as our corporate secretary considers appropriate.


Our corporate secretary may decide in the exercise of his or her judgment whether a response to any stockholder or interested party communication is necessary.

This procedure for stockholder and other interested party communications with the non-management directors is administered by our nominating and governance committee. This procedure does not apply to (a)(i) communications to non-management directors from our officers or directors who are stockholders or (b)(ii) stockholder proposals submitted pursuant to Rule 14a-8 under the Exchange Act.


Director Attendance at Annual Meetings

We do not have a formal policy regarding attendance by members of our board of directors at annual meetings of stockholders. We encourage, but do not require, directors to attend. All eleven members of our board of directorsmembers serving at the time of our 20172019 annual meeting attended our 20172019 annual meeting.


Code of Business Conduct and Ethics

Our board of directors has adopted a written code of business conduct and ethics that applies to our directors, officers and employees, including our principal executive officer, principal financial officer, principal accounting officer orand controller, or persons performing similar functions. A copy of the code of business conduct and ethics is available on the corporate governance section of our website, which is located at http://ir.vitaltherapies.com/corporate-governance.ir.imux.com. If we make any substantive amendments to, or grant any waivers from, the code of business conduct and ethics for any officer or director, we will disclose the nature of such amendment or waiver on our website.


Director Compensation

Policy

In May 2013,July 2019, our board of directors adopted and approved a compensation policy for our non-employee directors, which was subsequently amended on March 2015, December 2015 and May 2016, which provides for the following compensation to our non-employee directors:

following:

Cash Compensation

Under our outside director compensation policy, all non-employee directors are entitled to receive the following cash compensation for their services:

each non-employee director receives an annual base retainer of $35,000 except that the Non-Executive Chairman of the Board receives an annual base retainer of $50,000;
in addition to the annual base retainer, the chairman of our audit committee receives an annual fee of $15,000 and other members of our audit committee receive an annual fee of $7,500;

- 20-





in addition to the annual base retainer, the chairmen of our other committees receive an annual fee of $10,000 and other members of our other committees receive an annual fee of $5,000;
in addition to the fees listed above, each non-employee director shall receive a per-meeting attendance fee of $500 for attending telephonic meetings of the board. In addition, each Outside Director will be paid a per-meeting attendance fee of $2,500 for attending in-person meetings of the board in excess of four during each calendar year.

·each non-employee director receives an annual base retainer of $35,000 except that the non-executive Chairman of the Board receives an annual base retainer of $65,000;

·in addition to the annual base retainer, the chairman of our audit committee receives an annual fee of $15,000 and other members of our audit committee receive an annual fee of $7,500;

·in addition to the annual base retainer, the chairmen of our other committees receive an annual fee of $10,000 and other members of our other committees receive an annual fee of $5,000; and

·each non-employee director receives a per-meeting attendance fee of $500 for attending telephonic meetings of the board.

All cash payments to non-employee directors are paid quarterly in arrears on a prorated basis. We also reimburse our directors for their reasonable expenses incurred in connection with attending board and committee meetings.

Equity Compensation

In addition to cash compensation, our non-employee directors are also entitled to equity awards under our outside director compensation policy. Each non-employee director who first joins us will beis automatically granted an initial award of a nonstatutorynon-statutory stock option with a Black-Scholes value of approximately $250,0000.2% of the Company’s outstanding shares on the date of grant. In addition, on the date of each annual meeting of stockholders, (commencing with this annual meeting of stockholders), each non-employee director who has been a non-employee director for 6 months or more on the date of the annual meeting will be automaticallyis granted an annual award of a nonstatutorynon-statutory stock option with a Black-Scholes value of approximately $125,000, or $175,000 for the non-executive chairman0.2% of the board,Company’s outstanding shares on the date of grant. The initial award will vestvests in 48 equal monthly installments subject to the director’s continued service with us.the Company. The annual award will vestvests in full on the earlier to occur of the one-year anniversary of its grant date or the day prior to the next annual meeting of stockholders, subject in each case to continued service with us.

In the event of a “change of control,” as defined in our 2014 Equity Incentive Plan, with respectCompany.


Director Compensation

Our compensation committee retained Aon Hewitt to awards granted under the 2014 Equity Incentive Plan to outside directors, the participant outside director will fully vest in and have the right to exercise awards as to all shares underlying such awards regardless of performance goals, vesting criteria, or other conditions.

In May 2017, our board granted eachprovide recommendations on non-employee director a stock option to purchase 45,022 shares, or 63,031 sharescompensation based on an analysis of market data compiled from comparable companies in the case of Mr. Satter, who at that time was the non-executive chairman of the board, of our common stock at an exercise price of $3.20, which will vest in full on the earlier to occur of the one-year anniversary of its grant date or the day prior to the next annual meeting of stockholders subject to continued service with us. In connection with his appointment to non-executive chairman of our board of directors in September 2017, Mr. Hasnain was granted an option to purchase 15,222 shares of our common stock at an exercise price of $3.15 per share, which will vest in full on the earlier of (i) the one-year anniversary of its grant date or (ii) the day prior to the next annual meeting of Vital Therapies’ stockholders, subject to his continued service with us.


- 21-





Director Compensation Table
biotechnology industry. The following table summarizes compensation paid to our non-employee directors during or with respect to the fiscal year ended December 31, 2017.

Name Fees Earned or Paid in Cash ($) Option
Awards
($) (1)
  All Other
Compensation ($) (2)
 Total ($)
Jean-Jacques Bienaimé 46,000 102,547(3) 
 148,547
Cheryl L. Cohen 46,000 102,547(4) 
 148,547
Philip M. Croxford 45,500 102,547(5) 
 148,047
Douglas E. Godshall 48,000 102,547(6) 
 150,547
Errol R. Halperin 53,500 102,547(7) 
 156,047
Faheem Hasnain 55,833 136,537(8) 
 192,370
J. Michael Millis, M.D. 51,000 102,547(9) 38,750
 192,297
Muneer A. Satter 55,667 143,566(10) 
 199,233
Lowell E. Sears 56,000 102,547(11) 
 158,547
Randolph C. Steer, M.D., Ph.D. 51,000 102,547(12) 
 153,547
2019.

Name

Fees Earned or Paid in Cash

($)

Option Awards

($)(1)

 

All Other Compensation

($)

Total

($)

Dr. Duane Nash (Chair)43,850264,800 308,650
Jan Van den Bossche40,415264,800 305,215
Tamar Howson11,250183,444 194,694
Dr. Jörg Neermann39,240264,800 304,040
Dr. Vincent Ossipow38,615264,800 303,415
Barclay Phillips12,500146,288 158,788
(1)The amounts in the “Option Awards” column reflect the aggregate grant date fair value of stock options granted during the calendar year computed in accordance with the provisions of Accounting Standards Codification 718, Compensation – Stock Compensation.ASC 718. The assumptions that we used to calculate these amounts are discussed in Note 79 to our consolidated financial statements appearing at the end of ourthis Annual Report on Form 10-K for the year ended December 31, 2017.Report. These amounts do not reflect the actual economic value that will be realized by the director upon the vesting of the stock options, the exercise of the stock options, or the sale of the common stock underlying such stock options. As of December 31, 2017, Dr. Winters, our Chief Executive Officer had outstanding and unexercised option awards for 686,672 shares.
(2)Dr. Millis was paid an aggregate of $38,750 in consideration for services as a consultant and for services rendered as chair of our Clinical Advisory Board in fiscal year 2017.
(3)Mr. Bienaimé had a total of 147,225 stock options outstanding as of December 31, 2017.
(4)Ms. Cohen had a total of 79,202 stock options outstanding as of December 31, 2017.
(5)Mr. Croxford had a total of 111,416 stock options outstanding as of December 31, 2017.
(6)Mr. Godshall had a total of 167,043 stock options outstanding as of December 31, 2017.
(7)Mr. Halperin had a total of 111,924 stock options outstanding as of December 31, 2017.
(8)Mr. Hasnain had a total of 118,818 stock options outstanding as of December 31, 2017.
(9)Dr. Millis had a total of 106,059 stock options outstanding as of December 31, 2017.
(10)Mr. Satter had a total of 93,270 stock options outstanding as of December 31, 2017.
(11)Mr. Sears had a total of 167,043 stock options outstanding as of December 31, 2017.
(12)Dr. Steer had a total of 122,400 stock options outstanding as of December 31, 2017.


Mr. Cox is not eligible to receive any board compensation because he is an employee. In addition, Terence E. Winters, Ph.D., who was our Chief Executive Officer and Co-chairman during 2017, did not receive any board compensation because he was an employee. We reimburse our directors for their reasonable expenses incurred in connection with attending board and committee meetings.

- 22-





PROPOSAL NUMBER 1



ELECTION OF CLASS IIII DIRECTORS

Our board of directors is currently composed of elevenseven directors and is divided into three staggered classes of directors. At the annual meeting, threetwo Class I directorsIII Directors will be elected to our board of directors by the holders of our common stock. As two Class I directors are not standing for reelection, our board of directors will be composed of nine directors following the 2018 Annual Meeting. Each director’s term continues until our 2023 annual meeting and the election and qualification of his or her successor, or such director’s earlier death, resignation or removal.

Certain of our stockholders affiliated with Mr. Satter, referred to as the Satter Investors, currently have contractual rights to nominate up to 30% of our directors, as provided in the Senior Preferred IRA. To date, the Satter Investors have not exercised their rights to designate any candidates for nomination but have reserved the right to do so in the future. As the Satter Investors’ ownership percentage decreases, their right to nominate directors decreases.

Nominees for Director

Our nominating and governance committee recommended for nomination and our board of directors nominated Jean-Jacques Bienaimé, Russell J. CoxDr. Ossipow and Errol R. Halperin, as nomineesMr. Van den Bossche for election as Class I directorsIII Directors at the annual meeting. If elected, each of Messrs. Bienaimé, Cox and Halperinthey will serve as Class I directorsIII Directors until the 20212023 annual meeting and until histheir respective successor issuccessors are duly elected and qualified. For more information concerning the nominees,Dr. Ossipow and Mr. Van den Bossche, please see the section entitled “Board of Directors and Corporate Governance.”

Messrs. Bienaimé, Cox

Dr. Ossipow and HalperinMr. Van den Bossche have agreed to serve if elected, and management has no reason to believe that they will be unavailable to serve. In the event a nomineethat either of them is unable or declines to serve as a director at the time of the annual meeting, proxies will be voted for any nomineenominees who may be proposed by the nominating and governance committee and designated by the present board of directors to fill the vacancy.

Required Vote

The Class I directorsIII Directors elected to the board of directors will be elected by a plurality of the votes cast by the holders of shares present in person or represented by proxy and entitled to vote on the election of directors. In other words, the three nominees thatif Dr. Ossipow and Mr. Van den Bossche receive the highest number ofa single “FOR” votesvote, they will be elected as Class I directors.III Director. Shares represented by executed proxies will be voted, if authority to do so is not expressly withheld, for the election of Jean-Jacques Bienaimé, Russell J. CoxDr. Ossipow and Errol R. Halperin.Mr. Van den Bossche. Broker non-votes will have no effect on this proposal.

Board Recommendation

Our board of directors recommends a vote “FOR” the election to the board of directors of Jean-Jacques Bienaimé, Russell J. CoxDr. Ossipow and Errol R. HalperinMr. Van den Bossche as Class I directors.III Directors.


PROPOSAL NUMBER 2



- 23-





RATIFICATION OF APPOINTMENT OF INDEPENDENT
REGISTERED PUBLIC ACCOUNTING FIRM

Our audit committee has appointed PricewaterhouseCoopersBaker Tilly Virchow Krause, LLP (“Baker Tilly”) as the independent registered public accounting firm to audit our consolidated financial statements for the year ending December 31, 2018. During 2017, PricewaterhouseCoopers LLP served as our independent registered public accounting firm.

2020.

Notwithstanding itssuch appointment and even if our stockholders ratify thesuch appointment, our audit committee, in its discretion, may appoint another independent registered public accounting firm at any time during the year if the audit committeeit believes that such a change would be in the best interests of Vital Therapiesthe Company and its stockholders. Our audit committee is submitting the appointment of PricewaterhouseCoopers LLPBaker Tilly to our stockholders because we value our stockholders’ views on our independent registered public accounting firmsuch appointment and as a matter of good corporate governance. If the appointment is not ratified by our stockholders, our audit committee may reconsider whether it should appointconsider appointing another independent registered public accounting firm. A representative of PricewaterhouseCoopers LLPBaker Tilly is expected to attend the annual meeting, where he or she will be available on the phone to respond to appropriate questions and, if he or she desires, to make a statement.


Fees Paid to the Independent Registered Public Accounting Firm

On April 12, 2019, the audit committee dismissed PricewaterhouseCoopers LLP (“PwC”) as the Company’s independent registered public accounting firm and approved the engagement of Baker Tilly as its new independent registered public accounting firm for the fiscal year ending December 31, 2019. In connection with the audit of the 2019 financial statements, we entered into an engagement agreement with Baker Tilly that set forth the terms by which Baker Tilly would perform audit services for the Company. Such engagement was approved in advance by our audit committee.

PwC’s reports on the Company’s consolidated financial statements for the years ended December 31, 2018 and 2017 did not contain an adverse opinion or disclaimer of opinion, and were not qualified or modified as to uncertainty, audit scope or accounting principles, except that PwC’s reports for the fiscal year ended December 31, 2018 included an explanatory paragraph indicating that there was substantial doubt about the Company’s ability to continue as a going concern.

During the Company’s two most recent fiscal years ended December 31, 2018 and 2017 and the subsequent interim period through April 12, 2019: (i) there were no disagreements between the Company and PwC on any matters of accounting principles or practices, financial statement disclosure, or auditing scope or procedure, which disagreements, if not resolved to the satisfaction of PwC, would have caused it to make reference to the subject matter of the disagreements in connection with its reports on the Company’s consolidated financial statements; and (ii) there were no “reportable events” (as described in Item 304(a)(1)(v) of Regulation S-K).

The following table represents aggregate fees for services provided to us in the fiscal years ended December 31, 2017 and 20162019 by PricewaterhouseCoopers LLP,Baker Tilly, our principal accountant. All fees below were pre-approved by the audit committee:


 Fiscal Year Ended
 2017 2016
Audit Fees (1)$547,621
 $486,895
Audit-related Fees (2)
 
Tax Fees (3)
 
All Other Fees (4)1,800
 1,800
Total Fees$549,421
 $488,695

  Fiscal Year Ended
  

2019

($) 

 

2018

($)

Audit Fees(1)  533,002    
Audit-related Fees      
Tax Fees      
All Other Fees(2)  94,000    
Total Fees  627,002    
(1)Audit fees consist of fees incurred for professional services by PricewaterhouseCoopers LLPBaker Tilly for audit and quarterly reviews of our financial statements, reviews of our registration statements on Form S-3 and Form S-8 and related services that are normally provided in connection with statutory and regulatory filings or engagements.

(2)We did not engage PricewaterhouseCoopers LLP to perform audit-related services.
(3)We did not engage PricewaterhouseCoopers LLP to perform tax advisory services.
(4)Represents annual licensing fees for an accounting database subscription.related to issuance of comfort letters.
In connection with the audit of the 2017 financial statements, we entered into an engagement agreement with PricewaterhouseCoopers LLP that sets forth the terms by which PricewaterhouseCoopers LLP will perform audit services for us. Such engagement was approved in advance by our audit committee.


- 24-





Auditor Independence

In 2017,2019, there were no other professional services provided by PricewaterhouseCoopers LLPBaker Tilly that would have required our audit committee to consider their compatibility with maintaining the independence of PricewaterhouseCoopers LLP.

Baker Tilly.


Pre-Approval Policy

Our audit committee’s policy is to pre-approve all audit and permissible non-audit services provided by the independent accountants. These services may include audit services, audit-related services, tax services and other services. Our audit committee generally pre-approves particular services or categories of services on a case-by-case basis. The independent registered public accounting firm and management are required to periodically report to our audit committee regarding the extent of services provided by the independent registered public accounting firm in accordance with these pre-approvals, and the fees for the services performed to date. All of the services of PricewaterhouseCoopers LLPBaker Tilly for 20172019 and 20162018 described above were pre-approved by our audit committee.


Required Vote

Ratification of the appointment of PricewaterhouseCoopers LLPBaker Tilly as our independent registered public accounting firm for the year ending December 31, 20182020 requires the affirmative “FOR” vote of a majority of the shares present in person or represented by proxy at the annual meeting and entitled to vote on the proposal. You may vote “FOR,” “AGAINST,” or “ABSTAIN” on this proposal. Abstentions have the same effect as a vote against the proposal. Broker non-votes will not affect the outcome of voting on this proposal.


Board Recommendation

Our board of directors recommends a vote “FOR” the ratification of the appointment of PricewaterhouseCoopers LLPBaker Tilly as our independent registered public accounting firm for the year ending December 31, 2018.

2020.



- 25-






Report of the Audit Committee

The audit committee (which, as of the date below, is composed of the undersigned directors) is a committee of the board of directors comprised solely of independent directors as required by the listing standards of Nasdaq and rules and regulations of the SEC. The audit committee operates under a written charter approved by Vital Therapies’our board of directors, which is available on Vital Therapies’Immunic’s web site at http://ir.vitaltherapies.com/corporate-governance.ir.imux.com/documents-and-charters. The audit committee held sixfour meetings during fiscal year 2017.2019. The meetings of the audit committee are designed to facilitate and encourage communication among the audit committee, the company,Company, and the company’sCompany’s independent auditor. The composition of the audit committee, the attributes of its members and the responsibilities of the audit committee, as reflected in its charter, are intended to be in accordancecomply with applicable requirements for corporate audit committees. The audit committee reviews and assesses the adequacy of its charter and the audit committee’sits performance on an annual basis.

With respect to Vital Therapies’our financial reporting process, Vital Therapies’our management is responsible for (1)(i) establishing and maintaining internal controls and (2)(ii) preparing Vital Therapies’our consolidated financial statements. Vital Therapies’our independent registered public accounting firm PricewaterhouseCoopers LLP, or PwC, is responsible for performing an independent audit of Vital Therapies’our consolidated financial statements in accordance with the auditing standards of the Public Company Accounting Oversight Board (United States) (“PCAOB”), or PCAOB, and to issue a report thereon. It is the responsibility of the audit committee to oversee these activities. Specifically, the audit committee is responsible for the appointment, compensation, and general oversight of the external auditor, as well as fee negotiations with the external auditor. It is not the responsibility of the audit committee to prepare Vital Therapies’Immunic’s financial statements. These are the fundamental responsibilities of management. In the performance of its oversight function, the audit committee has:

reviewed and discussed the audited financial statements for fiscal year 2017 with the management of Vital Therapies;
discussed with PwC, Vital Therapies’ independent registered public accounting firm, the matters required to be discussed by Auditing Standard No. 16, Communications with Audit Committees, as amended (AICPA, Professional Standards, Vol. 1, section 380), and as adopted by the PCAOB in Rule 3200T; and
received the written disclosures and the letter from PwC as required by applicable requirements of the PCAOB regarding the independent registered public accounting firm’s communications with the audit committee concerning independence, and has discussed with PwC that firm’s independence.

·reviewed and discussed the audited financial statements for fiscal year 2019 with the management of Immunic;

·discussed with Baker Tilly the matters required to be discussed by Auditing Standard No. 16, Communications with Audit Committees, as amended (AICPA, Professional Standards, Vol. 1, section 380), and as adopted by the PCAOB in Rule 3200T; and

·received the written disclosures and the letter from Baker Tilly as required by applicable requirements of the PCAOB regarding Baker Tilly’s communications with the audit committee concerning independence, and has discussed with Baker Tilly its independence.

Based on the audit committee’s review of theour audited financial statements and the various discussions with management and PwC,Baker Tilly, the audit committee recommended to the board of directors that theour audited financial statements be included in our annual report on Form 10-K for the fiscal year ended December 31, 20172019 for filing with the SEC. The audit committee has also appointed PwC as the company’s independent registered public accounting firm for the year ending December 31, 2018.

The Audit Committee
Lowell E. Sears (Chair)
Douglas E. Godshall
Errol R. Halperin

- 26-





This report of the audit committee shall not be deemed to be “soliciting material” or to be “filed” with the SEC or subject to Regulation 14A promulgated by the SEC or Section 18 of the Exchange Act, and shall not be deemed incorporated by reference into any prior or subsequent filing by Vital TherapiesImmunic under the Securities Act of 1933, as amended or the Securities Act,(the “Securities Act”) or the Exchange Act, except to the extent Vital TherapiesImmunic specifically requests that the information be treated as “soliciting material” or specifically incorporates it by reference.

Barclay Phillips, Chair

Jan Van den Bossche

Dr. Jörg Neermann


- 27-







EXECUTIVE OFFICERS

The names of our executive officers, their ages, their positions with Vital TherapiesImmunic and other biographical information as of March 29, 2018April 15, 2020, are set forth below. There are no family relationships among any of our directors and executive officers.


Name Age Position
Russell J. CoxDr. Daniel Vitt51Chief Executive Officer, President, Director
Dr. Manfred Gröppel 51Chief Operating Officer
Dr. Hella Kohlhof47Chief Scientific Officer
Dr. Andreas Muehler 54 Board Member and Chief ExecutiveMedical Officer
Duane D. Nash, M.D., J.D.Glenn Whaley 4752 President
Robert A. Ashley, M.A.60Executive Vice PresidentPrincipal Financial and Chief TechnicalAccounting Officer
Michael V. Swanson, M.B.A.63Executive Vice President and Chief Financial Officer
Aron P. Stern, M.B.A.64Chief Administrative Officer
John M. Dunn, J.D.66General Counsel and Secretary
Andrew Henry53Vice President, Clinical Operations
Richard Murawski69Vice President, Manufacturing
Russell J. Cox. Please see

Dr. Manfred Gröppel. Dr. Manfred Gröppel joined Immunic in April 2016. As part of the biographical information above in the section entitled “Board of Directorssenior management team, he has been serving as Chief Operating Officer and, Corporate Governance – Nomineesuntil April 2019, acting Chief Financial Officer leading functional responsibility for Director.”

Duane D. Nash, M.D., J.D. has served as our President since March 2016. Between March 2012accounting, finance, risk management and Marchlegal. From April 2016 to December 2016, he served as ourImmunic’s interim Chief Executive Officer. Previously, he was Head of Business Officer,Development at 4SC AG where he managed worldwide business development activities since 2001 and he served as our Executive Vice President between May 2013project leader of the development team for IMU-838. Prior to joining 4SC, Dr. Gröppel held various positions at Tripos Inc., where he managed business development activities in Central and March 2016. Between March 2012South Europe, Scandinavia and May 2013,Israel. He also worked at the Research Center Siemens from 1994 to 1997. Dr. Gröppel brings to Immunic more than 18 years of business development leadership and a strong scientific background in drug discovery, product development, manufacturing processes, chemistry, manufacturing and controls (CMC) and project valuation. Dr. Gröppel’s successful track record of licensing transactions in the healthcare industry worldwide totals more than 300 million USD and includes Yakult Honsha’s acquisition of resminostat, Link Health’s acquisition of 4SC-205, out-licensing the APAC rights for resminostat to Menarini, and the acquisition of eight oncology projects from Altana. Recently, he also served as our Medical Director.successfully negotiated an option and licensing agreement for Immunic’s IMU-856 with Daiichi Sankyo. Dr. Nash completed his internship in general surgeryGröppel studied chemistry at the University Erlangen-Nuremberg, Germany and received his doctorate in chemistry from the Institute of CaliforniaOrganic Chemistry, University Erlangen-Nuremberg. He has been a guest speaker at San Francisco during which he servedseveral national and international conferences and has been awarded several patents related to IMU-838

Dr. Hella Kohlhof. Dr, Kohlhof joined Immunic in 2017. She studied biology in Aachen, Gothenborg (Sweden) and Munich and received her Doctorate in Biology form the Ludwig Maximiliams University of Munich (Germany). During her Ph.D. and post-doctoral position at the Institute of Clinical Molecular Biology and Tumor Genetics at the Helmholtz Centre in Munich, she worked on the normal and malignant B cell development influenced by Notch and Epstein Barr Virus mediated signaling. In 2008 she joined 4SC AG as a memberresearch scientist and group leader and established the research laboratory for translational pharmacology. She worked on 4SC’s preclinical and clinical stage projects from the oncology and immunology field, including IMU-838 and IMU-366. From 2011 on Dr. Kohlhof was responsible for the management and development of 4SC’s epigenetic clinical stage small molecule inhibitor 4SC-202. In early 2015, as Director of Development Projects, she took over responsibility for the liver transplant team.complete development portfolio of 4SC AG. Dr. NashKohlhof has a strong scientific background in the immunology and oncology field and is experienced in drug development, preclinical and translational pharmacology, clinical trial design and bio-marker development.

Dr. Andreas Muehler. Dr. Muehler joined Immunic in August 2016. Dr. Muehler received his medical degree (MD) from Humboldt-University in Berlin, Germany, and an MBA degree from Duke University. After a short period in clinical work, Dr. Muehler has worked within the pharmaceutical industry since 1992, mostly in the U.S., with leadership positions in preclinical and clinical development, business development and licensing and marketing. Since 2003, Dr. Muehler developed and managed multiple medical companies in the U.S. Among them were 3TP LLC d/b/a CAD Sciences (White Plains, NY), a medical software company developing an imaging solution for early detection of breast and prostate cancer, and Cellectar Inc. (Madison, WI), a biotech company developing new cancer therapeutics and cancer imaging agents. Dr. Muehler was also practiced as an attorney from November 2002 to February 2008, most recently at the law firmPresident CEO of Davis Polk, where he focusedMicroMRI Inc. (Langhorne, PA), a medical device company developing solutions for improved osteoporosis diagnosis and therapy monitoring based on intellectual property litigation and corporate matters. Dr. Nash joined Vital Therapies from Wedbush PacGrow Life Sciences where he was employed from March 2009 to March 2012 serving most recently as a Vice President in Equity Research. Before that he was a research analyst at Pacific Growth Equities from April 2008 through March 2009, which was subsequently acquired by Wedbush Securities, Inc. Dr. Nashbone micro-architecture. He has servedbeen on the board of directors of Akebia Therapeutics, Inc.multiple small medical technology companies. After moving to Munich in 2009, Dr. Muehler became managing director of the small healthcare private equity fund Palladius Healthcare GmbH (Munich, Germany), a publicly-traded biotech company focused on the treatment of anemiawhich acquired distressed medical technology companies. Thereafter, Dr. Muehler worked as interim manager and vascular disease, since May 2013. He served on the board of directors of Aerpio Therapeutics Inc., a clinical-stage biopharmaceutical company focused on advancing innovative therapiesindependent senior medical consultant with multiple assignments for vascular diseases, from September 2012 to March 2017. Dr. Nash earned a B.A. in biology from Williams College, an M.D. from Dartmouth Medical School, a J.D. from the University of California, Berkeley, and an M.B.A. from the University of Oxford.

Robert A. Ashley, M.A. has served as our Executive Vice President and Chief Technical Officer since September 2013. Between May 2008 and September 2013 he served as our Vice President and Chief Operating Officer. Mr. Ashley’s careerclients in the pharmaceutical industry extendsand medical device industries.


Glenn Whaley. Mr. Whaley joined Immunic as Principal Accounting Officer and Controller in December 2019. In April 2020, he was promoted to the position of Vice President Finance, Principal Financial and Accounting Officer. Mr. Whaley has more than 30 years. He was formerly Chairman, President and Chief Executive Officer of AmpliMed Corporation, a privately-held cancer drug development company, from January 2004 to March 2007, and Senior Vice President of Commercial Development at CollaGenex Pharmaceuticals, Inc., a publicly-held pharmaceutical company, from September 1994 to December 2003. Prior to that he held positions of increasing responsibility at Bristol-Myers Squibb from January 1989 to September 1994, and with Amersham International from


-28-





1979 to 1989. He earned a Master’s Degree in Biochemistry from Oxford University. Mr. Ashley is the inventor of several issued and pending patents, as well as the author of several scientific papers. He serves on the Board of Directors of Rowpar Pharmaceuticals, a privately-held manufacturer of proprietary dental pharmaceuticals.
Michael V. Swanson, M.B.A. joined us in August 2013 as our Chief Financial Officer and has also served as our Executive Vice President since March 2016. Mr. Swanson has over 20 years of experience in senior financial positions in both publicAccounting and private life sciences companies.Finance roles. Prior to joining us, Mr. SwansonWhaley was ChiefVice President of Finance at Pernix Therapeutics, a Branded and Generics Pharmaceutical Company, from March 2015 until May 2019. His responsibilities included Principal Financial and Accounting Officer, from November 2018 until May 2019, Principal Accounting Officer and Controller from December 2017 until November 2018 and Vice President of Amira Pharmaceuticals, Inc.,Financial Planning and Analysis from March 2015 until November 2017. Mr. Whaley was Vice President of Finance for Alvogen, Inc, a pharmaceutical company focused on the discovery and early development of drugs to treat inflammatory and fibrotic diseases,Global Pharmaceutical Company, from May 20082011 until the company was acquired in September 2011, and of Panmira Pharmaceuticals, LLC, a spin out from Amira from September to December 2011. From January 2012 to October 2015, Mr. Swanson provided financial consulting services to development stage companies. From July 2000 to April 2008, Mr. Swanson served in senior finance positions including SeniorMarch 2015. His responsibilities included Vice President Finance of U.S. Operations from August 2013 to March 2015 and Chief Financial Officer at Prometheus Laboratories Inc., a specialty pharmaceutical company marketing and selling pharmaceutical products and diagnostic testing services for gastrointestinal diseases and disorders. Previously,Global Corporate Controller from May 2011 to August 2013. Prior to Alvogen, Mr. Swanson was Senior Vice President and Chief Financial Officer of Advanced Tissue Sciences, Inc., a publicly-traded biomedical company, where he served in senior financial positions for over ten years. Mr. Swanson alsoWhaley served as Director of Finance of the Fisher Scientific Group, Inc.,Corporate Controller for ImClone Systems, a health and scientific technologybiopharmaceutical company and its parent, The Henley Group, Inc., a widely diversified holding company. Mr. Swanson began his career working approximately nine years with the public accounting firm of Deloitte Haskins & Sells, now Deloitte & Touche LLP. Mr. Swanson earned a B.S. in business administration from the California Polytechnic State University at San Luis Obispo and an M.B.A. from the University of Southern California. He is also a Certified Public Accountant (inactive).
Aron P. Stern, M.B.A. has served as our Chief Administrative Officer since August 2013 and as our Secretary from October 2005dedicated to February 2015. Between June 2003 and August 2013, Mr. Stern served as our Treasurer, Vice President and Chief Financial Officer. Mr. Stern has over 20 years of experience in capital formation, acquisitions, financial strategy and financial and operational management in growth-stage high technology and biotechnology companies. He previously was Chief Financial Officer at each of Protein Polymer Technologies, Inc., a developer of a protein-based technology, 4-D Neuroimaging, a medical equipment manufacturing company, and VitaGen, Inc., our predecessor company. Mr. Stern also held positions at Apple Computer and Isis Pharmaceuticals, a developer of antisense drugs. Mr. Stern earned a B.S. in economics and business administration and an M.B.A. in finance and marketing from the University of California, Berkeley.
John M. Dunn, J.D. has served as our General Counsel since November 2014 and as our Secretary since February 2015. Mr. Dunn has over 25 years of national law firm and in-house general counsel experience. Mr. Dunn was Senior Vice President Legal and Compliance, General Counsel and Secretary of IDEC Pharmaceuticals from 2002 until its merger with Biogen in late 2003. From 2004 to 2012, Mr. Dunn served as an Executive Vice President at Biogen Idec where he was in charge of Biogen Idec’s internal corporate venture fund and Innovation Incubator. More recently, Mr. Dunn was providing legal and corporate development advisory services to emerging life science companies. Previously, Mr. Dunn was a partner for 16 yearsdeveloping biologic medicines in the Corporate, Securities and Technology Group at the Pillsbury Winthrop law firm where his practice focused on the healthcare industry. Mr. Dunn earned a B.S. in finance and his J.D.area of oncology, from the University of Wyoming. He serves as an advisorJanuary 2007 to TVM Capital, a life science venture capital firm, and is a member of the board of directors of Acer Therapeutics, Inc., a publicly-traded specialty orphan pharmaceutical company.

- 29-





Andrew Henry has served as our Vice President of Clinical Operations since April 2013. Mr. Henry is responsible for the global implementation of our clinical program. Mr. Henry has over 25 years of experience managing clinical trials in life science companies with roles at Schering-Plough Oncology, Novartis Oncology and MedImmune. Between January 2009 and February 2013, Mr. Henry served as Senior Director of Clinical Trial ManagementMay 2011 and Senior Director of Global Clinical Operational StrategyFinancial Reporting from January 2005 to December 2006. Prior to ImClone Systems, Mr. Whaley served in financial rolls at increasing levels of MedImmune, a biopharmaceutical company that is under AstraZeneca’s biologics division. At MedImmune, Mr. Henry oversaw operations of all clinical studies being performed by the company across all therapeutic areas. From November 1997 to August 2008, Mr. Henry held roles as Senior Clinical Research Scientist and Head Clinical Resources and Development Director at Novartis Oncology, an ethical pharmaceutical company, where he oversaw clinical studiesresponsibility in public accounting and the Departmentpharmaceutical and telecommunications industries. Mr. Whaley holds a Bachelor of Clinical Research Scientists/Clinical Trial Heads. Mr. Henry earnedScience degree from Rutgers University Business School and is a B.S. in biology and biopsychology from William Paterson University.
Richard Murawski has served as our Vice PresidentMember of Manufacturing since July 2013. Mr. Murawski has more than 40 years of experience in manufacturing facility design, construction, start-up, validation, and supply chain management, both domestically and internationally, including 17 major plant start-ups. From February 2013 to July 2013, Mr. Murawski was self-employed as a consultant. From June 2010 to February 2013, Mr. Murawski served as the Vice President/General Manager for Dendreon Corporation, a biotech manufacturing company, with responsibility for, among others, manufacturing, engineering, materials management, and facilities. Between June 2008 and July 2010, Mr. Murawski served as Chief Executive Officer of Murawski and Associates, a biotech consulting company, where he consulted companies on managing operations and biopharmaceutical facilities. From June 2002 to July 2008, Mr. Murawski served as Senior Vice President of Operations and Corporate Officer of Favrille, Inc., a biotech manufacturing company, and was responsible for manufacturing, engineering, materials management, facilities, technical services, and environmental, health and safety functions. Mr. Murawski earned his B.S. in chemical engineering from the Newark College of Engineering at the New Jersey Society of Certified Public Accountants and the American Institute of Technology.
Certified Public Accountants.

Biographical information for Dr. Daniel Vitt is set forth above in the section titled “Board of Directors and Corporate Governance.”



- 30-





EXECUTIVE COMPENSATION


Processes and Procedures for Executive Compensation

Our compensation committee assists theour board of directors in discharging the board’sits responsibilities relating to oversight of the compensation of our chief executive officer and our other executive officers, including reviewing and making recommendations to the board with respect to the compensation, plans, policies and programs for our chief executive officer and our other executive officers and administering our equity compensation plans for our executive officers and employees.

Our compensation committee annually reviews the compensation, plans, policies and programs for our chief executive officer and our other executive officers. In connection therewith, our compensation committee considers, among other things, each executive officer’s performance in light of established individual and corporate goals and objectives and the recommendations of our chief executive officer. In particular, our compensation committee considers the recommendations of our chief executive officer when reviewing base salary and incentive performance compensation levels of our executive officers and when setting specific individual and corporate performance targets under our annual executive incentive bonus plan for our executive officers. Our chief executive officer has no input and is not present during voting or deliberations about his compensation. Our compensation committee may delegate its authority to a subcommittee, but it may not delegate any power or authority required by agreement, law, regulation or listing standard to be exercised by the compensation committee as a whole.

Our nominating and governance committee has authority to review and recommend to the board compensation programs for our outside directors, although this role has been predominantly undertaken by our compensation committee, in consultation with members of our full board. Management generally does not have a role in the setting of director compensation. Our nominating and governance committee may delegate its authority to a subcommittee, but it may not delegate any power or authority required by agreement, law, regulation or listing standard to be exercised by the nominating and governance committee as a whole.

From time to time, our compensation committee has engaged Aon Hewitt, an independent compensation consulting firm, to evaluate our levels and types of executive and director compensation and to recommend changes as appropriate. Among other objectives, Aon Hewitt has assisted the compensation committee in identifying a peer group of companies based on our company’s current stage of development for the comparison of executive and director compensation, and has also provided to the compensation committee comparative data on executive and director compensation practices in our industry and general advice on our executive and director compensation programs. In December 2015 and again in January 2017, Aon Hewitt completed a comprehensive review of our executive and director compensation programs in order to align our policies with those of similarly-sized public companies in the biotechnology industry and to ensure that our executive and director compensation programs provide sufficient recruitment and retention incentives as well as incentives to achieve our long-term strategic business objectives. For purposes of its January 2017 review, our compensation committee, in consultation with Aon Hewitt, updated our peer group data to reflect our current status. The compensation committee consults regularly with Aon Hewitt in connection with specific aspects of or questions relating to our executive and director compensation.

The compensation committee has the sole authority to approve the terms of theany engagement of Aon Hewitt. Although our board of directors and compensation committee consider the advice and


- 31-





recommendations of our independent compensation consultants as to our executive and director compensation programs, our board of directors and compensation committee ultimately make their own decisions about these matters.
Aon Hewitt did not provide any services to us or our compensation committee other than as described above.

The compensation committee has a policy for compensation consultant independence under whichthat requires any compensation consultant retained by the compensation committee mustto be independent of the companyCompany and management. The compensation committee has reviewed the independence of Aon Hewitt in light of this policy, SEC rules and Nasdaq listing standards regarding compensation consultants and has concluded that Aon Hewitt’s work for the compensation committee does not raise any conflict of interest.


Summary Compensation Table

Our named executive officers for the year ended December 31, 2017, which consist of our principal executive officer and our two other most highly compensated executive officers,2019 are Terence E. Winters, Ph.D.,Dr. Daniel Vitt, our Chief Executive Officer until December 31, 2017,and President; Dr. Manfred Gröppel, our Chief Operating Officer; Dr. Andreas Muehler, our Chief Medical Officer; Russel J. Cox, our former Chief Executive Officer; and Dr. Duane D. Nash M.D., J.D.,in his capacity as our President, and Robert A. Ashley ourformer Chief Executive Vice President and Chief Technology Officer.

Name and Principal Position Year Salary
($)
 Option
Awards
($) (1)
 Non-Equity
Incentive
Plan
Compensation
($) (2)
 All Other
Compensation
($) (3)
 Total
($)
Terence E. Winters, Ph.D. 2017 504,700 902,170 219,746 550,551
 2,177,167
Chief Executive Officer 2016 490,000 586,400 73,500 18,808
 1,168,708
Duane D. Nash, M.D., J.D. 2017 400,000 193,647 177,496 
 771,143
President 2016 375,550 498,440 67,820 
 941,810
Robert A. Ashley 2017 381,100 170,865 158,200 
 710,165
Executive Vice President and Chief Technical 2016 370,000 439,800 83,528 
 893,328
Officer

            

Name and Principal PositionYear

Salary

($)(4)

Option Awards

($)

Stock Awards

($)

Non-Equity Incentive Plan Compensation ($)All Other Compensation ($)

Total

($)

Dr. Daniel Vitt2019202,275573,8011,495,870111,9862,383,932
Chief Executive Officer, President2018
        
Dr. Manfred Gröppel2019137,649176,5541,495,87055,9931,866,067
Chief Operating Officer2018
        
Dr. Andreas Muehler2019177,772353,1371,495,87079,43411,8582,118,072
Chief Medical Officer2018
        
Russell J. Cox (2)20195,711468,045202,134540,0001,215,890
Former Chief Executive Officer2018572,6267,080,630330,00073,4338,056,689
        
Duane D. Nash, M.D., J.D. (3)2019120,983264,800223,706165,920188,789964,198
Former Chief Executive Officer2018414,800294,73743,615753,152
(1)
The amounts in the “Option Awards” column reflect the aggregate grant date fair value of stock options granted during the calendar year computed in accordance with the provisions of Accounting Standards Codification 718, (“ASC 718”)Compensation - Stock Compensation. The assumptions that we used to calculate these amounts are discussed in Note 9 to our financial statements appearing at the end of this Annual Report. These amounts do not reflect the actual economic value that will be realized by the named executive officer upon the vesting of the stock options, the exercise of the stock options, or the sale of the common stock underlying such stock options. The shares subject to the stock options vest monthly over four years, subject to the named executive officers’ continued service on each such date, and are otherwise subject to the terms of our 2014 Equity Incentive Plan, or 2014 Plan, and form of option agreement for our 2014 Plan. The 2017 amount for Dr. Winters includes $674,350 of stock-based compensation recorded in conjunction with Dr. Winters’ transition agreement.

(2)2017 and 2016 amounts approved by our board of directors onMr. Cox resigned as Chief Executive Officer in January 30, 2018 and 2017, respectively.2019.

(3)“All Other Compensation” consists of company-paid reimbursement for MedicareDr. Nash resigned as Chief Executive Officer in April 2019 in connection with the Exchange Transaction.

(4)Dr. Vitt and prescription drug coverage and, in 2017, theDr. Gröppel received payment of certain legal fees. In addition, 2017 includes severance coststheir salary in Euros. Dr. Muehler received payment in both USD and Euros. An exchange rate of $525,100 payable1 Euro to Dr. Winters pursuant1.12 USD, based on the average exchange rate for 2019, was used to Dr. Winters’ transition agreement.convert payment amounts in Euros for the table above

Non-Equity Incentive Plan Compensation and Bonus

Executive Incentive Compensation Plan

- 32-





Our Executive Incentive Compensation Plan, or Incentive Plan, was adopted

We offer our NEOs the opportunity to earn annual discretionary cash bonuses, as determined by our board of directors on July 8, 2013. Our Incentive Plan is administered by our compensation committee; provided, however, that our board of directors must approve any award or any amendment to any award made thereunder. Ourthe compensation committee determines the performance goals applicable to any award, which goals may include, without limitation, the attainment of research and development milestones, sales bookings, business divestitures and acquisitions, cash flow, cash position, earnings (which may include earnings before interest and taxes, earnings before taxes and net earnings), earnings per share, net income, net profit, net sales, operating cash flow, operating expenses, operating income, operating margin, overhead or other expense reduction, product defect measures, product release timelines, productivity, profit, return on assets, return on capital, return on equity, return on investment, return on sales, revenue, revenue growth, sales results, sales growth, stock price, time to market, total shareholder return, working capital, and individual objectives or other subjective or objective criteria. Performance goals that include the company’s financial results may be determined in accordance with United States generally accepted accounting principles, or GAAP, or such financial results may consist of non-GAAP financial measures. The performance goals may be on an individual, divisional, business unit, functional or company-wide basis. The performance goals may differ from participant to participant and from award to award.

Pursuant to the employment letter agreements entered into between us andannually at their discretion. Actual bonus amounts for our named executive officers, our named executive officersNEOs are each eligible to receive annual bonuses as a percentage of their annual base salary based upon achievement of the performance goals determined by our compensation committee. committee after consideration of Dr. Vitt’s recommendations (except with respect to his individual bonus). Our CEO makes recommendations to the compensation committee regarding annual bonus payouts for the executive officers other than himself and does not participate in any discussions with the compensation committee regarding his own compensation.


For additional information regarding2019, annual bonuses were based on such factors as the terms of these employment letter agreements, see below under “Agreements With Our Named Executive Officers.”

Notwithstanding the eligibility for bonus awards, our board of directors may, in its sole discretion and at any time, increase, reduce or eliminatethe compensation committee deemed appropriate, including a participant’s actual award, or increase, reduce or eliminate the amount allocatedvariety of individual and Company priorities and objectives relating to the bonus pool for a particular2019, as well as each individual NEO’s performance period. The actual award may be below, at or above a participant’s target award, in the discretion of our board. Our board may determine the amount of any reduction on the basis of such factors as it deems relevant,related to his area of responsibility.

In the fourth quarter of 2019, the board approved a 100% bonus payout for 2019 to each of Dr. Vitt, Dr. Mühler, and it is not required to establish any allocation or weighting with respect to the factors it considers.

Actual awards areDr. Gröppel. The bonuses were paid in cash only after they are earned, which usually requires continued employment through the date of payment of the award. Payment of bonuses occurs as soon as administratively practicable after they are earned, but no later than the dates set forth in the Incentive Plan.
Our board of directors has the authority to amend, alter, suspend or terminate the Incentive Plan provided such action does not impair the existing rights of any participant with respect to any earned bonus.
For the fiscal year ended December 31, 2017, bonus awards for our named executive officers were based on the achievement of corporate performance goals, which carried a 60% weighting, and individual performance, which carried a 40% weighting, except with respect to Dr. Winters for whom a bonus award was based solely on the achievement of corporate performance goals. Our compensation committee established the categories of corporate performance goals as relating to the attainment of research and development milestones and financings. Our compensation committee determined that the performance goals of our named executive officers were met at a range of 87% to 92% of target, and payments were approved at those payout percentages by our board on January 30, 2018.

- 33-





2019.

Agreements With Our Named Executive Officers

Terence E. Winters

Dr. Daniel Vitt

On September 4, 2019, Dr. Daniel Vitt and Immunic AG entered into an amendment to the Service Agreement (as amended, the “Amended Vitt Agreement”), dated September 29, 2016. Pursuant to the Amended Vitt Agreement, Dr. Vitt will continue to serve on the management board of Immunic AG until August 31, 2021. Dr. Vitt will receive an annual salary of EUR 300,000, to be paid in 12 monthly installments, and a yearly bonus of EUR 100,000 upon achievement of certain targets.

Dr. Andreas Muehler

On September 4, 2019, Immunic AG entered into an amendment to the Service Agreement (as amended, the “Amended Muehler Agreement”), dated August 22, 2016, between Immunic AG and Dr. Andreas Muehler, our Company’s Chief Medical Officer. Pursuant to the Amended Muehler Agreement, Dr. Muehler will continue to serve on the management board of Immunic AG until August 31, 2021. Dr. Muehler will receive an annual salary of EUR 140,000, to be paid in 12 monthly installments, and a yearly bonus of EUR 42,000 upon achievement of certain targets.

On September 4, 2019, Dr. Muehler also entered into a separate employment agreement (the “Muehler Employment Agreement”) with the Company. The Muehler Employment Agreement provides that Dr. Muehler will continue to serve as Chief Medical Officer until August 31, 2021, and will dedicate approximately 40% of his time to the affairs of the Company and approximately 60% of his time to the affairs of Immunic AG. The Muehler Employment Agreement provides for an annual salary of $180,000 USD and an annual bonus of at least 18% of annual base salary upon achievement of certain targets. Dr. Muehler will also receive an inaugural equity award of an option to purchase 40,000 shares of Company common stock. Dr. Muehler is also eligible for reimbursement for certain expenses, and customary insurance and benefits programs of the Company.

If Dr. Muehler’s employment is terminated by the Company without Cause or by him for Good Reason (each as defined in the Muehler Employment Agreement), he is entitled to (i) twelve months’ base salary, (ii) any accrued but unpaid annual bonus for the fiscal year ended prior to termination, and (iii) reimbursement of certain COBRA premiums. Additionally, all of his outstanding equity awards will vest and become exercisable.

Dr. Manfred Gröppel

On September 4, 2019, Immunic AG entered into an amendment to the Service Agreement (as amended, the “Amended Gröppel Agreement”), dated August 29, 2016, between Immunic AG and Dr. Manfred Gröppel, the Company’s Chief Operating Officer. Pursuant to the Amended Gröppel Agreement, Dr. Gröppel will continue to serve on the management board of Immunic AG until August 31, 2021. Dr. Gröppel will receive an annual salary of EUR 200,000, to be paid in 12 monthly installments, and a yearly bonus of EUR 50,000 upon achievement of certain targets.

Russell J. Cox

We entered into an employment letter agreement, dated October 31, 2013,November 30, 2017, with Dr. Winters,Mr. Cox, which setsset forth the terms and conditions of his employment with us.the Company. The employment letter agreement had no specific term and provided for at-will employment. This agreement superseded all existing agreements he may have with us concerning his employment relationship. Prior to his resignation in December 2017, Dr. Winters’Mr. Cox’s annual base salary was $504,700,$540,000 and he was awarded a signing bonus of $330,000 payable within 30 days of his start date of January 3, 2018, and he was eligible for an annual target bonus equal to 50% of his base salary.

Effective December 31, 2017, Terence E. Winters, Ph.D. resigned as our Chief Executive Officer and as a member of our board of directors. In The agreement terminated in connection with his resignation, we entered into a transition agreement and release with the Exchange Transaction in April 2019.


Dr. Winters in which we agreed to pay Dr. Winters cash severance equal to his monthly base salary as currently in effect for 12 months following his termination date, pay Dr. Winters his achieved 2017 performance bonus, pay or reimburse Dr. Winters for his health coverage up to $1,700 per month for up to 12 months following his termination date, and extend the option exercise period for his outstanding Vital Therapies stock options up to the full maximum term (subject to earlier termination under the applicable equity incentive plan).

In addition, Dr. Winters agreed to provide transition consulting services (not to exceed 20 hours per week) at a rate of $250 per hour pursuant to a consulting agreement that is attached as an exhibit to the transition agreement and release. The consulting agreement has an initial 12-month term. Stock options held by Dr. Winters will continue to vest and remain exercisable in accordance with their terms during Dr. Winters’ consultancy term; provided, however, that if Vital Therapies terminates his consulting term early or fails to renew the agreement after the initial 12 month term, then 100% of any unvested shares subject to Dr. Winters’ stock options will vest and become exercisable.
Duane D. Nash

We entered into an employment letter agreement, dated October 30, 2013, with Dr. Nash, our current President, which setsset forth the terms and conditions of his employment with us.the Company. The employment letter agreement hashad no specific term and providesprovided for at-will employment. This agreement supersedes all existing agreements he may have with us concerning his employment relationship. Dr. Nash’s current annual base salary is $400,000,was $414,800, and he iswas eligible for an annual bonus equal to 40% (increased to 50% for 2017) of his annual base salary.

Robert A. Ashley
We entered into an employment letter The agreement dated October 30, 2013,terminated in connection with Mr. Ashley, our current Executive Vice Presidentthe Exchange Transaction in April 2019.

Potential Payments Upon Termination or Change in Control

NEOs After the Exchange Transaction

Dr. Vitt is entitled to severance of one year’s salary and Chief Technology Officer, which sets fortha bonus upon (i) the terms and conditionsconclusion of his employment with us. The employment letter agreement has no specific term and provides for at-will employment. Mr. Ashley’s current annual base salary is $381,100, and he is eligible for an annual bonus equal to 35% (increased to 45% for 2017)of service under the Amended Vitt Agreement, as such term may be amended or extended, or (ii) the termination of his annual base salary.



- 34-





Executive Changeservice before August 31, 2020, in each case provided that such non-extension or termination is not due to serious cause.

Dr. Muehler is entitled to severance of Controlone year’s salary and Severance Agreements

a bonus upon (i) the conclusion of his term of service under the Amended Muehler Agreement, as such term may be amended or extended, or (ii) the termination of his service before August 31, 2020, in each case provided that such non-extension or termination is not due to serious cause.

Dr. Gröppel is entitled to severance of one year’s salary and a bonus upon (i) the conclusion of his term of service under the Amended Gröppel Agreement, as such term may be amended or extended, or (ii) the termination of his service before August 31, 2020, in each case provided that such non-extension or termination is not due to serious cause.

The equity awards granted to our NEOs provide for accelerated vesting in connection with a change in control in limited circumstances, as described below.

NEOs Prior to the Exchange Transaction

We have entered into a change of control and severance agreement with each of our executive officers,Mr. Cox and Dr. Nash which requiresrequired us to make payments if the executive officer’stheir employment with us iswas terminated in certain circumstances.

If In January 2019, the compensation committee of the board of directors restructured these severance arrangements in an effort to advance and support our pursuit of strategic alternatives.

In connection with the restructuring, the compensation committee approved (i) the cancellation of options held by our executive officers; (ii) amendments to the prior change of control and severance agreements with such executive officers; and (iii) grants of restricted stock units to such executive officers, contingent upon them entering into all agreements necessary to effectuate these transactions. Under such agreements, Mr. Cox and Dr. Nash cancelled outstanding options for 1,588,832 shares and 613,391 shares, respectively, and were granted 1,854,376 and 886,316 restricted stock units, respectively. All such restricted stock units vested in connection with the Exchange Transaction.

Under the amended change of control and severance agreements (the “Vital Agreements”), if prior to the two-monthsix-month period before or after the twelve-month period following a change of control (such period, the Change“Change of Control Period)Period”), anthe executive officer’s employment iswas terminated without “cause” or an executive officer resigns for “good reason” (as such terms are defined in the change of control and severance agreement)Vital Agreements), such officer will bewas eligible to receive the following benefits if such officerupon timely signssigning and does not revokerevoking a release of claims:

·a lump sum payment equal to his base salary for a period of six months (12 months in the case of Mr. Cox);

·reimbursement by us for up to six months (12 months in the case of Mr. Cox) of COBRA premiums to continue health insurance coverage for such officer and such officer’s eligible dependents, or taxable monthly payments for the equivalent period in the event payment for COBRA premiums would violate applicable law; and

·100% accelerated vesting of all outstanding equity awards.


continued payment of base salary for a period of six months (12 months in the case of Mr. Cox); and
reimbursement by us for up to six months (12 months in the case of Mr. Cox) of COBRA premiums to continue health insurance coverage for such officer and such officer’s eligible dependents, or taxable monthly payments for the equivalent period in the event payment for COBRA premiums would violate applicable law.

If, within the Change of Control Period, such officer’s employment iswas terminated without cause or such officer resigns for good reason, such officer will bewas entitled to the following benefits if such officerupon timely signssigning and not revoking a release of claims:

a lump sum payment equal to (x) 12 months (18 months in the case of Mr. Cox) his annual base salary (for the year of the change of control or such officer’s termination, whichever is greater), plus (y) 1x (1.5x in the case of Mr. Cox) the greater of: (A) such officer’s target annual bonus (for the year of the change of control or such officer’s termination, whichever is greater) or (B) such officer’s actual bonus for performance relating to the calendar year immediately prior to the calendar year of such officer’s termination;
reimbursement by us for up to 12 months (18 months in the case of Mr. Cox) of COBRA premiums to continue health insurance coverage for such officer and such officer’s eligible dependents, or taxable monthly payments for the equivalent period in the event payment for COBRA premiums would violate applicable law; and
100% accelerated vesting of all outstanding equity awards.

·a lump sum payment equal to (x) 12 months (18 months in the case of Mr. Cox) his annual base salary (for the year of the change of control or such officer’s termination, whichever is greater), plus (y) 1.0x (1.5x in the case of Mr. Cox) the greater of: (A) such officer’s target annual bonus (for the year of the change of control or such officer’s termination, whichever is greater) or (B) such officer’s actual bonus for performance relating to the calendar year immediately prior to the calendar year of such officer’s termination, less (z) an amount equal to the grant date fair value of the January 2019 restricted stock unit award;

·reimbursement by us for up to 12 months (18 months in the case of Mr. Cox) of COBRA premiums to continue health insurance coverage for such officer and such officer’s eligible dependents, or taxable monthly payments for the equivalent period in the event payment for COBRA premiums would violate applicable law; and

·100% accelerated vesting of all outstanding equity awards.

In addition, in the event any of the amounts provided for under these agreements or otherwise payable to our executive officers would constitute “parachute payments” within the meaning of Section 280G of the Internal Revenue Code and could be subject to the related excise tax, the executive officer would bewas entitled to receive either full payment of benefits under this agreement or such lesser amount which would result in no portion of the benefits being subject to the excise tax, whichever results in the greater amount of after-tax benefits to the executive officer. The agreements dodid not require us to provide any tax gross-up payments.

The option grants to Drs. Winters and

Mr. Cox resigned as Chief Executive Officer in January 2019. In connection with his resignation, Mr. Cox received severance of $540,000.

Dr. Nash and Mr. Ashley and other executive officers made pursuant to our 2014 Plan provide for accelerated vestingresigned as Chief Executive Officer in April 2019 in connection with a change in control in limited circumstances, as described below.


- 35-





2014the Exchange Transaction. Pursuant to the Vital Agreements, Dr. Nash received severance of $188,789.

2019 Omnibus Equity Incentive Plan

Our 20142019 Omnibus Equity Incentive Plan (the “Plan”) provides that in the event of a merger or change in control,Corporate Transaction, as defined in the 2014 Plan, each outstanding award will be treated as the administrator determines, including, without limitation, that(i) with respect to unvested awards, may beunless such awards are assumed or substituted for by the acquiring or succeeding corporation or replaced with equivalent awards, the administrator will cancel such awards or accelerate their vesting, and (ii) with respect to vested awards, the administrator may be terminated immediately(a) allow grantees to exercise such awards within a reasonable period prior to the consummation of the merger or change in control,Corporate Transaction and cancel any outstanding awards may vest in whole or in part prior to orthat remain unexercised upon consummation of the mergerCorporate Transaction, or change in control and, to the extent the administrator determines, terminate on(b) cancel any or immediately prior to the effectivenessall of the merger or change in control, orsuch outstanding awards may be terminated in exchange for cash or property or replaced with other rights or property. If a successor corporation does not assume or substitute an equivalent award for any outstanding award, then such award will fully vest, all restrictions on such award will lapse and all performance goals or other vesting criteria applicable to such award will be deemed achieved at one hundred percent (100%) of target levels. Additionally, if a successor corporation does not assume or substitute an option or stock appreciation right, the administrator will notify the participant in writing or electronically that such award will be exercisable for a specified period of time determined by the administrator priorpayment equal to the transaction, and such award will then terminate uponamount that the expiration of such period.grantee would have received.


In addition, pursuant to their stock option agreements, certain optionees, including our named executive officers who have awards under the 2014 Plan, are eligible for full vesting acceleration of their outstanding options in the event their service is terminated other than for cause within twelve months following a change in control.

2012 Stock Option Plan and Option Agreements
Our 2012 Plan provides that in the event of a change in control, as defined in the 2012 Plan, the surviving, continuing successor, or purchasing corporation or other business entity or parent thereof may assume or substitute an equivalent award for each outstanding option under the 2012 Plan. If there is no assumption or substitution of outstanding options, such options will terminate upon the expiration of a stated notice period unless otherwise specified in the applicable stock option agreement.
In addition, pursuant to their stock option agreements, certain optionees are eligible for full vesting acceleration of their outstanding options in the event their service is terminated other than for cause or they resign from their service for good reason, in either case, within twelve months following a change in control. Furthermore, if there is no assumption or substitution of outstanding options following a change in control and, provided further that, such optionee’s service has not terminated prior to such change in control, such outstanding options are eligible for full vesting acceleration as of the date ten days prior to the date of the change in control and will terminate upon the expiration of the stated notice periodunless exercised or terminated in exchange for cash or property.


- 36-





cause.

Outstanding Equity Awards at Fiscal Year-End for Fiscal 2017

2019

The following table sets forth certain information concerning outstanding equity for our named executive officers awarded at fiscal year-end December 31, 2017:


Name and Position Vesting
Commencement
Date
 Number of
Securities
Underlying
Unexercised
Options
Exercisable
 Number of
Securities
Underlying
Unexercised
Options
Unexercisable
 Option
Exercise
Price
 Option
Expiration
Date
Terence E. Winters, Ph.D.  
 
9/13/2012
      
 
      386,672
      
 
      —
      
 $8.00
 
9/25/2022
      
Chief Executive Officer

 
10/9/2018(1)

 

 
100,000

 $4.57
 
10/8/2025

  4/16/2016(2) 41,666 58,334 $8.28
 5/12/2026
  6/10/2017(2) 12,500 87,500 $3.20
 6/9/2027
Duane D. Nash, M.D.  
 
2/8/2012
      
 
      93,377
      
 
      —
      
 $0.43
 
3/31/2022
      
President

 
4/25/2012
      

 
23,344
      
 
      

 $0.43
 
4/24/2022
      

  
9/13/2012
      
 
241,670
      
 
      

 $8.00
 
9/25/2022
      

  
10/9/2018(1)

 

 
75,000

 $4.57
 
10/8/2025

  4/16/2016(2) 35,416 49,584 $8.28
 5/12/2026
  6/10/2017(2) 10,625 74,375 $3.20
 6/9/2027
Robert A. Ashley  
 
2/8/2012
      
 
      93,377
      
 
      —
      
 $0.43
 
3/31/2022
      
Executive Vice President and Chief

 
4/25/2012
      
 
23,344
      
 
      

 $0.43
 
4/24/2022
      
Technical Officer

 
9/13/2012
      

 
241,670
      
 
      

 $8.00
 
9/25/2022
      

  
10/9/2018(1)

 

 
75,000

 $4.57
 
10/8/2025

  4/16/2016(2) 31,250 43,750 $8.28
 5/12/2026
  6/10/2017(2) 9,375 65,625 $3.20
 6/9/2027
2019.

    OPTION AWARDS STOCK AWARDS
Name 

Vesting Commencement Date

(1)

 

Securities Underlying Unexercised Options Exercisable

(#)

 

Securities Underlying Unexercised Options Unexercisable

(#)

 

Option Exercise Price

($)

 Option Expiration Date 

Unvested Shares or Units

(#)

 

Market Value of Unvested Shares or Units

($)

Dr. Daniel Vitt 08/01/19 0 65,000 13.29 8/1/2029  
Chief Executive Officer, President              
               
Dr. Manfred Gröppel  08/01/19 0 20,000 13.29 8/1/2029  
Chief Operating Officer              
               
Dr. Andreas Muehler 08/01/19 0 30,000 13.29 8/1/2029  
Chief Medical Officer 08/12/19 0 10,000 13.34 8/12/2029    
               
Russell J. Cox (2)       
Former Chief Executive Officer              
               
Duane D. Nash, M.D., J.D. 07/22/19 6,934 23,025 13.63 7/22/2029  
Former Chief Executive Officer (3)              
(1)100% of the shares subject to theseAll options willgranted in August 2019 vest 25% on the thirdfirst anniversary of the vesting commencement date and then in monthly installments over the following 36 months.

(2)All restricted stock units held by Mr. Cox vested in connection with the Exchange Transaction.

(3)9,986 of the options vest in monthly increments over a period of one year from the grant date, ifand 19,973 of the VTL-308 clinical trial has achieved statistical significanceoptions vest in monthly increments over a period of at least p≤0.05 in the primary efficacy end point by, and the participant continues to be a service provider through, the third anniversary ofthree years from the grant date.
(2)These options vest in equal monthly installments over the four year period following the vesting commencement.


Perquisites, Health, Welfare and Retirement Benefits

Our named executive officers in the U.S. are eligible to participate in our employee benefit plans, including our medical, (except for Dr. Winters who had company-reimbursed Medicare and prescription drug coverage), dental, vision, group life, disability and accidental death and dismemberment insurance plans, in each case on the same basis as all of our other employees. We provide a 401(k) savings plan to our employees, including our current named executive officers, as discussed in the section below entitled “401(k) Savings Plan.”

Our NEOs in Germany receive health benefits through the German national healthcare system.

We generally do not provide perquisites or personal benefits to our named executive officers, except in limited circumstances and as noted in the Summary Compensation Table above. Our board of directors may elect to adopt qualified or non-qualified benefit plans in the future if it determines that doing so is in our best interests.



- 37-





401(k) Plan

We maintain a tax-qualified retirement plan that provides eligible U.S. employees, including named executive officers, with an opportunity to save for retirement on a tax advantaged basis. All participants’ interests in their deferrals are 100% vested when contributed. Pre-tax and after-tax contributions are allocated to each participant’s individual account and are then invested in selected investment alternatives according to the participant’s directions. Currently, we do not make matching contributions into the plan. The 401(k) plan is intended to qualify under Sections 401(a) and 501(a) of the Internal Revenue Code. As a tax-qualified retirement plan, pre-tax contributions to the 401(k) plan and earnings on those contributions are not taxable to the employees until distributed from the 401(k) plan, and all companymatching contributions, if any, are deductible by us when made.


Equity Compensation Plans

The following table summarizes information about our equity compensation plans as of December 31, 2017.2019. All outstanding option awards relate to our common stock.


Plan Category Number of Securities to be Issued Upon Exercise of Outstanding Options, Warrants and Rights (a) Weighted-Average Exercise Price of Outstanding Options,
Warrants and Rights (b)
 Number of Securities Remaining Available for Future Issuance Under Equity Compensation Plans
(excluding securities reflected in column (a)) (c)
Equity compensation plans approved by security holders:      
  2012 Stock Option Plan 2,596,405
 $6.84
 
  2014 Equity Incentive Plan (1) 3,487,077
 $6.70
 125,000
Equity compensation plans not approved by security holders:         
  
  Amended & Restated 2017 Inducement Equity Incentive Plan 
 
 1,850,000
Total 6,083,482
 $6.76
 1,975,000

Plan Category 

Number of Securities to Be

Issued Upon Exercise of

Outstanding Options,

Warrants and Rights

(a)

 

Weighted-Average Exercise

Price of Outstanding Options,

Warrants and Rights

(b)

 

Number of Securities Remaining

Available for Future Issuance Under

Equity Compensation Plans (excluding securities reflected in column (a))

(c)

Equity compensation plans approved by security holders:            
2019 Omnibus Equity Compensation Plan  456,645  $12.57   1,043,355 
Assumed Vital Equity Compensation Plans  14,403  $306.01   89,561 
Equity compensation plans not approved by security holders:          
             
Total  471,048       1,132,916 
(1)Our 2014 Equity Incentive Plan provides for an annual increase in the number of shares available for issuance thereunder on each anniversary dateequal to 4% of our initial public offering, equal to the lower of: (i) 1,200,000 shares of our common stock; (ii) 3% of theissued and outstanding shares of our common stock on a fully-diluted basis as of the second-to-last day prior to each anniversary date; or (iii) an amountend of the immediately preceding fiscal year (or such lesser number as our board of directors may determine.determine).


- 38-





Compensation Committee Report

The compensation committee (which, as of the date below, is composed of the undersigned directors) has reviewed and discussed the foregoing “Executive Compensation” section of this proxy statement with management. Based on this review and discussion, the compensation committee recommended to our board of directors that such information be included in this proxy statement.

The Compensation Committee

Randolph C. Steer, M.D., Ph.D. (Chair)
Jean-Jacques Bienaimé
Faheem Hasnain
Muneer A. Satter
The information contained inreport of the Compensation Committee Reportcompensation committee shall not be deemed to be soliciting material“soliciting material” or to be filed“filed” with the SEC noror subject to Regulation 14A promulgated by the SEC or Section 18 of the Exchange Act, and shall such informationnot be deemed incorporated by reference into any futureprior or subsequent filing by Immunic under the Securities Act or the Exchange Act, except to the extent Immunic specifically requests that Vital Therapiesthe information be treated as “soliciting material” or specifically incorporates it by reference in such filing.
reference.

Tamar Howson, Chair

Dr. Jörg Neermann


- 39-







RELATED PERSON TRANSACTIONS


Related Person Transactions

The following is a summary of transactions since

Since January 1, 2017 to which2019, we have not been a party to any transactions in which the amount involved exceeded $120,000 and in which any of our executive officers, directors, promoters or beneficial holders of more than 5% of our capital stock had or will have a direct or indirect material interest, other than compensation arrangements which are described under the section of this proxy statement titled “Executive Compensation.”

Senior Preferred Investors’ Rights Agreement
We and certain of our directors, executive officers and stockholders, including the Satter Investors, are parties to the Senior Preferred IRA. The Senior Preferred IRA contains customary preemptive rights in favor of our stockholders party thereto, as well as customary registration rights and related provisions, including customary market standoff provisions. All preemptive rights in favor of our stockholders under the Senior Preferred IRA terminated upon the closing of our initial public offering.
The Senior Preferred IRA also provides that, for so long as the Satter Investors hold at least 30% of our outstanding common stock, the Satter Investors have the right to nominate 40% of our directors (rounded up to the nearest whole number). If the Satter Investors hold less than 30% (but at least 20%) of our outstanding common stock, they have the right to nominate 30% of our directors (rounded up to the nearest whole number). If the Satter Investors hold less than 20% (but at least 10%) of our outstanding common stock, they have the right to nominate 20% of our directors (rounded up to the nearest whole number). If the Satter Investors hold less than 10% (but at least 2%) of our outstanding common stock, they have the right to nominate 10% of our directors (rounded up to the nearest whole number). For so long as the Satter Investors hold less than 2% of our outstanding common stock, they do not have the contractual right to nominate any representatives to our board of directors. To date the Satter Investors have not exercised their rights to nominate any directors, but they have reserved the right to do so in the future.
Series D Investors’ Rights Agreement
We and certain of our directors, executive officers and stockholders, including the Satter Investors, are or were parties to an investors’ rights agreement, dated June 7, 2011, or the Series D IRA. The Series D IRA contains restrictions on transfer (for compliance with applicable securities laws) and customary registration rights. Upon the closing of our initial public offering in April 2014, all covenants in this agreement, except for the rights relating to the registration of shares under the Securities Act, terminated. The rights of any of our directors, officers or stockholders under the Series D IRA, who became parties to the Senior Preferred IRA, were superseded by the Senior Preferred IRA.

- 40-





Indemnification of Officers and Directors

We have also entered into indemnification agreements with each of our directors and executive officers. The indemnification agreements, and our amended and restated certificate of incorporation and amended and restated bylaws require us to indemnify our directors, executive officers and certain controlling persons to the fullest extent permitted by Delaware law.


Related-Person Transactions Policy

We adopted a written Related Person Transactions Policy that sets forth our policies and procedures regarding the identification, review, consideration, approval and oversight of “related person transactions.”

For purposes of our policy only, a “related-person transaction” is a past, present or future transaction, arrangement or relationship (or any series of similar transactions, arrangements or relationships) in which we and any “related person” are participants, the amount involved exceeds $120,000 and a related person has a direct or indirect material interest. Various transactions are not covered by this policy, including transactions involving compensation for services provided to us as an employee, director, consultant or similar capacity by a related person, equity and debt financing transactions with a related person that are approved by the Board, and other transactions not otherwise required to be disclosed under Item 404 of Regulation S-K. A “related person,” as determined since the beginning of our last fiscal year, is any executive officer, director or nominee to become director, a holder of more than 5% of our common stock, including any immediate family members of such persons. Any related-person transaction may only be consummated if approved or ratified by the affirmative vote of seventy-five percent (75%) of our dis-interesteddisinterested directors then in office in accordance with the policy guidelines set forth below.

Under the policy, where a transaction has been identified as a related-person transaction, management must present information regarding the proposed related-person transaction to our audit committee for review and recommendation for approval to our board of directors. In considering related-person transactions, our audit committee and board of directors take into account the relevant available facts and circumstances including, but not limited to whether the terms of such transaction are no less favorable than terms generally available to an unaffiliated third partythird-party under the same or similar circumstances and the extent of the related person’s interest in the transaction. In the event a director has an interest in the proposed transaction, the director must recuse himself or herself from the deliberations and approval process.


SECURITY OWNERSHIP

The following table sets forth the beneficial ownership of our common stock as of March 29, 201815, 2020 by:

each person, or group of affiliated persons, who we know to beneficially own more than 5% of our common stock;
each of our named executive officers;
each of our directors; and

- 41-





all of our executive officers and directors as a group.

·each person, or group of affiliated persons, who we know to beneficially own more than 5% of our common stock;

·each of our named executive officers;

·each of our directors; and

·all of our executive officers and directors as a group.

The percentage ownership information shown in the table is based on an aggregate of 42,368,86410,744,806 shares of our common stock outstanding as of March 29, 2018.

15, 2020.

We have determined beneficial ownership in accordance with the rules of the Securities and Exchange Commission. These rules generally attribute beneficial ownership of securities to persons who possess sole or shared voting power or investment power with respect to those securities. In addition, the rules include shares of common stock issuable pursuant to the exercise of stock options and warrants that are either immediately exercisable or exercisable on or before May 28, 2018,14, 2020 which is 60 days after March 29, 2018.15, 2020. These shares are deemed to be outstanding and beneficially owned by the person holding those options and warrants for the purpose of computing the percentage ownership of that person, but they are not treated as outstanding for the purpose of computing the percentage ownership of any other person. Unless otherwise indicated, the persons or entities identified in this table have sole voting and investment power with respect to all shares shown as beneficially owned by them, subject to applicable community property laws.

Unless otherwise noted below, the address of each of the individuals and entities named in the table below is c/o Vital Therapies,Immunic, Inc., 150101200 Avenue of Science,the Americas, Suite 200, San Diego, California 92128.New York, New York 10036. Beneficial ownership representing less than 1% is denoted with an asterisk (*).


 Number of Shares of Common Stock Beneficially Owned Percentage of Common Stock Beneficially Owned
5% Stockholders:   
Trusts and Other Entities Affiliated with Muneer A. Satter (1)11,597,719 27.2%
Victory Capital Management (2)2,925,886 6.9%
KCK Ltd. (3)2,788,181 6.6%
Named Executive Officers and Directors:   
Russell J. Cox                 — 
Terence E. Winters, Ph.D. (4)777,027 1.8%
Duane D. Nash, M.D. (5)430,364 1.0%
Robert A. Ashley (6)416,640 1.0%
Faheem Hasnain (7)256,091 *
Jean-Jacques Bienaimé (8)212,344       *
Cheryl L. Cohen (9)79,032       *
Philip M. Croxford (10)136,507       *
Douglas E. Godshall (11)236,418       *
Errol R. Halperin (12)211,341       *
J. Michael Millis, M.D. (13)123,739       *
Muneer A. Satter (1)11,597,719 27.2%
Lowell E. Sears (14)225,615       *
Randolph C. Steer, M.D., Ph.D. (15)124,087       *
All directors and executive officers as a group and certain former named executive officers (19 people) (16)15,412,576 33.9%

- 42-





(1)

  Number of Shares of Common Stock Beneficially Owned Percentage of Common Stock Beneficially Owned
5% Stockholders:    
Global Life Bioventure V S.à r.l.  1,371,494   12.67%
LSP V Coöperatieve U.A  2,162,782   19.98%
IBG Risikokapitalfonds II GmbH & Co. KG  788,256   7.28%
Eckenstein-Geigy-Stiftung  632,448   5.84%
Fund+ N.V.  1,371,494   12.67%
Named Executive Officers and Directors:        
Duane D. Nash, M.D., J.D.(1)  22,515   * 
Dr. Manfred Gröppel(2)  284,480   2.63%
Tamar Howson(3)  6,935   * 
Dr. Andreas Muehler(4)  284,480   2.63%
Dr. Jörg Neermann(5)  12,483   * 
Dr. Vincent Ossipow(6)  12,483   * 
Barclay Phillips(7)  6,935   * 
Jan Van den Bossche(8)  12,483   * 
Dr. Daniel Vitt(9)  369,177   3.41%
Russell J. Cox(10)  0   * 
         
All directors and executive officers as a group and certain former named executive officers (12 people)  7,622,925   12.07%

* Less than 1%.

(1) Consists of 10,032 shares of common stock and 12,483 options to purchase shares of common stock.

(2) Consists of 11,382,277 shares and warrants to acquire 122,172 shares that are held by the Muneer A. Satter Revocable Trust and various other trusts and entities for which Mr. Satter serves as trustee, investment advisor or manager and, in such capacity, has sole voting and dispositive control over all such shares and options to purchase 93,270 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.

(2)
The address of Victory Capital Management, Inc. is 4900 Tiedeman Road, 4th Floor, Brooklyn, OH 44144. Victory Capital is the beneficial owner of 2,925,886 shares of common stock held on behalf of numerous clients who have the right to receive and the power to direct the receipt of dividends from, or the proceeds of the sale of, such common stock, and Victory Capital disclaims any ownership associated with such rights. No client has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, more than 5% of the shares outstanding of common stock of the company. This information is based solely upon a Schedule 13G filed by Victory Capital Management, Inc. on February 8, 2018 for beneficial ownership as of December 31, 2017.
(3) The address of KCK Ltd. A/C KCK Ltd. is OMC Chambers, Wickhams Cay 1, Road Town, Tortola VG1110, British Virgin Islands. KCK Ltd., through a board of directors consisting of three or more persons, has sole voting and investment power with respect to 2,788,181 shares of common stock held through Groeppel Investments UG (haftungsbeschrankt), an entity controlled by KCK Ltd. This information is based solely upon a Schedule 13G filed by KCK Ltd. on February 13, 2017 for beneficial ownership as of December 31, 2016.
(4)Dr. Gröppel.

(3) Consists of 194,966 shares held by Terence E. Winters, 119,964 shares held by the Winters Family Trust, 427 shares that may be acquired pursuant to the exercise of warrants held of record by Terence E. Winters, and options to purchase 461,670 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.

(5) Consists of 8,224 shares held and options to purchase 422,140shares of common stock.


(4) Consists of shares of common stock that are exercisable or becoming exercisable within 60 daysheld through Xanomed UG (haftungsbeschränkt), an entity controlled by Dr. Muehler.

(5) Consists of March 29, 2018.

(6)Consists of 2,000 shares held and options to purchase 414,640 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(7)Consists of 181,943 shares held by Faheem Hasnain, 3,500 shares held by Faheem Hasnain Trust and options to purchase 70,648 shares of common stock that are exercisable or become exercisable within 60 days of March 29, 2018.
(8)Consists of 65,119 shares held and options to purchase 147,225 shares of common stock that are exercisable or becoming exercisable with 60 days of March 29, 2018.
(9)Consists of 3,500 shares held by the Cheryl L. Cohen Trust Under Agreement dated April 1, 2005, Cheryl L. Cohen Trustee and options to purchase 75,532 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(10)Consists of 25,091 shares held and options to purchase 111,416 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(11)Consists of 69,375 shares held and options to purchase 167,043 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(12)Consists of 89,417 shares held by Errol R. Halperin, 10,000 shares held by Errol Halperin IRA FBO Errol Halperin, and options to purchase 111,924 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(13)Consists of 17,680 shares held and options to purchase 106,059 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(14)Consists of 58,572 shares held and options to purchase 167,043 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(15)Consists of 1,550 shares held, 137 shares that may be acquired pursuant to the exercise of warrants, and options to purchase 122,400 shares of common stock that are exercisable or becoming exercisable within 60 days of March 29, 2018.
(16)Consists of 12,251,443 shares held or beneficially owned, 122,791 shares that may be acquired pursuant to the exercise of warrants, and options to purchase 3,038,342 shares of common stock that are or will be exercisable within 60 days of March 29, 2018.
options to purchase shares of common stock.

(6) Consists of options to purchase shares of common stock.

(7) Consists of options to purchase shares of common stock.

(8) Consists of options to purchase shares of common stock.

(9) Consists of shares of common stock held through Listrax UG (haftungsbeschränkt), an entity controlled by Dr. Vitt.

(10) Based on information provided by the Company’s transfer agent.



- 43-





OTHER MATTERS


Section 16(a) Beneficial Ownership Reporting Compliance

Section 16(a) of the Exchange Act requires our executive officers and directors, and persons who own more than 10% of a registered class of our equity securities, to file reports of ownership and changes of ownership on Forms 3, 4 and 5 with the SEC. Such directors, executive officers and 10% stockholders are required by SEC regulations to furnish us with copies of all Section 16(a) forms they file.

Based solely on our review of the copies of such forms we have received and written representations from certain reporting persons that they filed all required reports, we believe that other than as set forth below, all of our officers, directors and greater than 10% stockholders complied with all Section 16(a) filing requirements applicable to them with respect to transactions during 2017.


2019.

On April 23, 2019, a Form 3 was filed one day late by Fund N.V.

One January 10, 2020, a Form 3 and Form 4 were filed approximately six weeks late for Glenn Whaley.

Fiscal Year 20172019 Annual Report

Our financial statements for our fiscal year ended December 31, 20172019 are included in our 20172019 annual report, which we will make available to stockholders at the same time as this proxy statement. This proxy statement and our 20172019 annual report are posted on our website at http://ir.vitaltherapies.com/www.imux.com and at the website of the Securities and Exchange Commission, or the SEC at www.sec.gov. You may also obtain a copy of our 20172019 annual report without charge by sending a written request to our Investor Relations departmentDepartment at Vital Therapies,Immunic, Inc., 150101200 Avenue of Science,the Americas, Suite 200, San Diego, California, 92128,New York, New York 10036, Attention: Investor Relations.


Company Website

We maintain a website at www.vitaltherapies.com.www.imux.com. Information contained on, or that can be accessed through, our website is not intended to be incorporated by reference into this proxy statement, and references to our website address in this proxy statement are inactive textual references only.


statement.

Availability of Bylaws

A copy of our bylaws may be obtained by accessing Vital Therapies’Immunic’s filings on the SEC’s website at www.sec.gov. You may also contact our corporate secretary at our principal executive offices for a copy of the relevant bylaw provisions regarding the requirements for making stockholder proposals and nominating director candidates.



- 44-





PROPOSALS OF STOCKHOLDERS FOR 20192021 ANNUAL MEETING


Stockholder Proposals for Inclusion in Proxy Statement

Stockholders may present proper proposals for inclusion in our proxy statement and for consideration at the next annual meeting of stockholders by submitting their proposals in writing to our corporate secretary in a timely manner. For a stockholder proposal to be considered for inclusion in our proxy statement for our next annual meeting of stockholders, our corporate secretary must receive the written proposal at our principal executive offices notno later than the close of business (5:30 p.m. Pacific Time) on December 13, 2018.April 2, 2021. In addition, stockholder proposals must comply with the requirements of Rule 14a-8 under the Exchange Act regarding the inclusion of stockholder proposals in company-sponsored proxy materials. Proposals should be addressed to:

Vital Therapies,

Immunic, Inc.
Attn: Corporate Secretary
150101200 Avenue of Science,the Americas, Suite 200
San Diego, California 92128
Fax: (858) 673-6843

New York, New York 10036

31 


Stockholder Proposals and Director Nominations Not for Inclusion in Proxy Statement

Our bylaws also establish an advance notice procedure for stockholders who wish to (i) present a proposal before an annual meeting of stockholders, but do not intend for the proposal to be included in our proxy statement and for stockholders toor (ii) nominate directors for election at an annual meeting of stockholders. In order to be properly brought before our 20192020 annual meeting of stockholders, the stockholder must have given timely notice of such proposal or nomination, in proper written form. To be timely for our 20192021 annual meeting of stockholders, a stockholder’s notice of a matter that the stockholder wishes to present, or the person or persons the stockholder wishes to nominate as a director, must be delivered to the corporate secretary of Vital Therapies at Vital Therapies’Immunic’s principal executive offices not less than 90 days and not more than 120 days prior to the first anniversary of the date of the preceding year’s annual meeting of stockholders. As a result, any written notice given by a stockholder pursuant to these provisions of our bylaws must be received by our corporate secretary at our principal executive offices:

not earlier than January 23, 2019, and
not later than February 22, 2019.

·not earlier than March 4, 2021, and

·not later than April 2, 2021.

In the event that we hold our 20192021 annual meeting of stockholders more than 30 days before or more than 30 days after the one-year anniversary date of the 20182021 annual meeting, then such written notice must be received no later than the close of business on the later of the following two dates:

the 90th day prior to such annual meeting, or
the 10th day following the day on which public announcement of the date of such meeting is first made.

- 45-





·the 90th day prior to such annual meeting, or

·the 10th day following the day on which public announcement of the date of such meeting is first made.

To be in proper written form, a stockholder’s notice must include the specified information concerning the proposal or nominee as described in our bylaws. Notices should be addressed to:

Vital Therapies,

Immunic, Inc.
Attn: Corporate Secretary
150101200 Avenue of Science,the Americas, Suite 200
San Diego, California 92128
Fax: (858) 673-6843

New York, New York 10036

For information on how to access our bylaws, please see the section entitled “Availability of Bylaws,” and for additional information regarding stockholder recommendations for director candidates, please see the section entitled “Board of Directors and Corporate Governance—StockholderGovernance-Stockholder Recommendations for Nominations to our Board.”

*********

We know of no other matters to be submitted at the 20182020 annual meeting. If any other matters properly come before the 20182020 annual meeting, it is the intention of the persons named in the proxy to vote the shares they represent as the board of directors may recommend. Discretionary authority with respect to such other matters is granted by a properly submitted proxy.

It is important that your shares be represented at the 20182020 annual meeting, regardless of the number of shares that you hold. You are, therefore, urged to vote as promptly as possible to ensure your vote is recorded.

THE BOARD OF DIRECTORS

San Diego, California
April 11, 2018

New York, New York
May 4, 2020





Important Notice Regarding the-Availability of Proxy Materials for the Shareholder Meeting of

IMMUNIC, INC.

To Be Held On:

July 2, 2020

via live webcast at https://web.lumiagm.com/276702602 (password: immunic2020)

COMPANYNUMBER
ACCOUNT NUMBER
CONTROL NUMBER

This communication presents only an overview of the more complete proxy materials that are available to you on the Internet.We encourage you to access and review all of the important information contained in the proxy materials before voting.

If 46you want-toreceiveapaperore-mail copyofthe proxy materials you must request one. Thereis nochargetoyou for requesting acopy.To facilitate timely delivery please make the request as instructed below before 6/19/20.

Please visithttp://www.astproxyportal.com/ast/22742/, where the following materials are available for view:

Notice of Annual Meeting of Stockholders


Proxy Statement

Form of Electronic Proxy Card

Annual Report on Form 10-K

TO REQUESTMATERIAL:

TELEPHONE: 888-Proxy-NA (888-776-9962) 718-921-8562 (for international callers)

E-MAIL:info@astfinancial.com

WEBSITE:https://us.astfinancial.com/OnlineProxyVoting/ProxyVoting/RequestMaterials

TO VOTE:

 

ONLINE:Toaccess your online proxy card, please visitwww.voteproxy.comand follow the on-screen instructions or scan the QR code with your smartphone.Youmay enter your voting instructions atwww.voteproxy.comup until11:59PM EasternTimethe day before thecut-offor meeting date.

VIRTUALLYAT THE MEETING:The company willbehosting the meeting live via the Internet thisyear.Toattendthemeetingvia theInternetplease visithttps://web.lumiagm.com/276702602(password: immunic2020) andbesuretohave available the controlnumber.

TELEPHONE:Tovote by telephone, please visitwww.voteproxy.comto view the materials and to obtain the toll free number to call.

MAIL:You may request a card by following the instructions above.

1.

Election of Directors for a term expiring at the 2023 Annual Meeting of Shareholders

 

NOMINEES:

2.

Ratification of appointment of BakerTillyVirchow Krause, LLP as independent auditors for fiscal year 2020 

 

Dr.VincentOssipow

JanVan den Bossche 

 

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE ELECTION OFDIRECTORSAND “FOR” PROPOSAL 2. 

    
    
    
    
    
    
    
 

Please note that you cannot use this notice to vote by mail.